Table 2 Correlation of CDH1 and CTNNB1 expression by IHC with clinicopathological factors, including patient and tumor characteristics, in esophageal cancer

Age at surgery

 <65 years

50

14

 >65 years

36

5

0.119

Gender

 Male

69

17

 Female

17

2

0.252

Tumor status

 T1

17

8

 T2

8

5

 T3

37

2

 T4

24

4

 T1 vs T2–4

0.006

Lymph node status

 N0

18

8

 N1

68

11

 N0 vs N1

0.010

Pathological stage

 I

13

6

 II

11

5

 III

28

3

 IV

34

5

 I–II vs III–IV

0.001

Lymphatic invasion

 Negative

16

9

 Positive

54

7

 Unknown

16

0.003

Blood vessel invasion

 Negative

30

11

 Positive

40

5

 Unknown

16

0.020