Prognostic relevance of autophagy-related markers LC3, p62/sequestosome 1, Beclin-1 and ULK1 in colorectal cancer patients with respect to KRAS mutational status

Table 3 Results of multivariate analysis (Cox regression) to determine the independent prognostic value of different variables in relation to tumour-specific overall survival in the complete cohort

Covariate	Relative risk	95 % CI	p value
p62	0.764	NS	0.619
Histological grading	1.239	NS	0.392
Lymph node metastases	0.794	NS	0.510
Tumour stage	1.647	NS	0.141
Distant metastases	3.176	1.453-6.940	0.004

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