Table 2 Univariate analysis (Kaplan-Meier, log-rank test) for prognostic significance of p62, histological grading, lymph node and distant metastases and tumour stage in relation to tumour-specific overall survival in the complete cohort

Cytoplasmic p62 (negative/positive)

0.043*

Cytoplasmic Beclin-1 expression (positive/negative)

0.464

Nuclear Beclin-1 expression (positive/negative)

0.106

Histological grading (G1-G3)

0.032*

Lymph node metastases (pN0 vs pN+)

<0.001*

Tumour stage (pT1-4)

<0.001*

Distant metastases (M0 vs M1)

<0.001*