Fig. 5
From: Damage effect of high-intensity focused ultrasound on breast cancer tissues and their vascularities
a The control group was positive for endothelial cell UEAI expression (endothelial cell marked with arrows, ×400 HPF). b The HIFU group was negative for endothelial cell UEAI expression (×400 HPF). c The average tumor capillaries, venules, and arterioles amount together 17.20 ± 3.50/vessels/HPF for the control group; vascular structure was destroyed for the HIFU group, with a vascular amount 0; UEAI staining was positive in control group, microvessel density count (MVD) was 51.18 ± 9.56/vessels/HPF, and UEAI staining was negative for the HIFU group, with a MVD of 0; the expression of vascular endothelial growth factor (VEGF) expression for the control group and HIFU group were 10.23 ± 2.20 and 1.31 ± 0.65, respectively; VEGF expression for the HIFU group remarkably decreased