Fig. 4From: Damage effect of high-intensity focused ultrasound on breast cancer tissues and their vascularities a Control group: integrity of internal and external elastic plates of blood vessels (elastic fiber marked with arrows, double histochemical staining of elastic fibers and collagen fibers in blood vessels: elastic fibers are blue, collagen fibers are red, background is pale yellow, tube diameter is 100 μm, ×400 HPF). b After HIFU treatment, elastic fiber disintegration is observed in blood vessels (elastic fiber marked with arrows, double histochemical staining of elastic fibers and collagen fibers in blood vessels: elastic fibers are blue, collagen fibers are red, background is pale yellow, tube diameter is 100 μm, ×400 HPF). c The diameters of the tumor blood vessels were all within 2000 μm in both groups, the majority of vascular diameter within 500 μm; smaller vascular diameter was positively correlated with more obvious damage by HIFUBack to article page