Fig. 1

The relative expression levels of miR-452 in osteosarcoma specimens and matched adjacent noncancerous bone tissues. a The fold change of miR-452 in osteosarcoma relative to the matched adjacent noncancerous bone tissues. b miR-452 expression was significantly lower in osteosarcoma specimens than in the corresponding adjacent noncancerous bone tissues. miR-452 levels were calculated by the 2^−ΔCt method and normalized to U6 small nuclear RNA