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Table 2 Comparison of imaging manifestations between BPNST and MPNST

From: Radiological findings of malignant peripheral nerve sheath tumor: reports of six cases and review of literature

 

BPNST (n = 28)

MPNST (n = 6)

P value

Mean ± SD average size (cm)

3.8 ± 1.4

7.2 ± 3.3

0.002a

Shape

  

0.640

  Oval or spindle

22 (78.6 %)

5 (83.3 %)

 

  Irregular

6 (21.4 %)

1 (16.7 %)

 

Margin

  

0.002a

  Ill-defined

1 (3.6 %)

4 (66.7 %)

 

  Well-defined

27 (96.4 %)

2 (33.3 %)

 

Eccentricity to the nerve

21 (75.0 %)

1 (16.7 %)

0.014a

Sign on MRI (MPNST (n = 5))

   

  Hypo-intense T1 and hyper-intense T2

20 (71.4 %)

4 (80 %)

0.052

  Mixed-intense T1 and T2

2 (7.2 %)

1 (20 %)

0.400

  Iso-intense T1 and hyper-intense T2

6 (21.4 %)

0 (0 %)

0.340

  T1 (homogenous)

10 (53.6 %)

4 (80 %)

0.089

  T2 (homogenous)

1 (3.6 %)

0 (0 %)

0.848

  Target sign

5 (17.9 %)

0 (0 %)

0.414

Split-fat sign

9 (32.1 %)

0 (0 %)

0.179

Intratumoral lobulation

2 (7.1 %)

4 (66.7 %)

0.004a

Cystic change

14 (50 %)

2 (33.3 %)

0.389

Perilesional edema-like zone

0 (0 %)

3 (50 %)

0.003a

Enhancement

   

  Peripheral with cystic change

4 (14.3 %)

4 (66.7 %)

0.018a

  Honeycomb-like

9 (32.1 %)

0 (0 %)

0.132

  Central

5 (17.9 %)

0 (0 %)

0.353

  Homogeneous

3 (10.7 %)

0 (0 %)

0.547

  Irregular

7 (25.0 %)

2 (33.3 %)

0.513

  1. aStatistically significant