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Table 2 Comparison of imaging manifestations between BPNST and MPNST

From: Radiological findings of malignant peripheral nerve sheath tumor: reports of six cases and review of literature

  BPNST (n = 28) MPNST (n = 6) P value
Mean ± SD average size (cm) 3.8 ± 1.4 7.2 ± 3.3 0.002a
Shape    0.640
  Oval or spindle 22 (78.6 %) 5 (83.3 %)  
  Irregular 6 (21.4 %) 1 (16.7 %)  
Margin    0.002a
  Ill-defined 1 (3.6 %) 4 (66.7 %)  
  Well-defined 27 (96.4 %) 2 (33.3 %)  
Eccentricity to the nerve 21 (75.0 %) 1 (16.7 %) 0.014a
Sign on MRI (MPNST (n = 5))    
  Hypo-intense T1 and hyper-intense T2 20 (71.4 %) 4 (80 %) 0.052
  Mixed-intense T1 and T2 2 (7.2 %) 1 (20 %) 0.400
  Iso-intense T1 and hyper-intense T2 6 (21.4 %) 0 (0 %) 0.340
  T1 (homogenous) 10 (53.6 %) 4 (80 %) 0.089
  T2 (homogenous) 1 (3.6 %) 0 (0 %) 0.848
  Target sign 5 (17.9 %) 0 (0 %) 0.414
Split-fat sign 9 (32.1 %) 0 (0 %) 0.179
Intratumoral lobulation 2 (7.1 %) 4 (66.7 %) 0.004a
Cystic change 14 (50 %) 2 (33.3 %) 0.389
Perilesional edema-like zone 0 (0 %) 3 (50 %) 0.003a
Enhancement    
  Peripheral with cystic change 4 (14.3 %) 4 (66.7 %) 0.018a
  Honeycomb-like 9 (32.1 %) 0 (0 %) 0.132
  Central 5 (17.9 %) 0 (0 %) 0.353
  Homogeneous 3 (10.7 %) 0 (0 %) 0.547
  Irregular 7 (25.0 %) 2 (33.3 %) 0.513
  1. aStatistically significant