Table 3 Univariate and multivariate analysis of factors associated with postoperative distant organ recurrence

Age

≥ 70

23

0.058

0.525

0.348

0.136–2.090

< 70

34

Reference

Gender

Male

42

0.418

Female

15

Surgical procedure

APR + TPE

20

0.812

Other operation

37

Histological depth of tumor

T0-2

19

0.404

T3, 4

38

Histological antitumor effect

G1

26

0.314

G2, 3

31

Histological type

por, muc

5

0.096

0.244

0.201

0.024–2.176

tub

52

Reference

Total radiation dose

40 Gy

14

0.524

50.4 Gy

43

Combination chemotherapy

5′DFUR

31

0.442

Capecitabine, S1

26

Pathological lymph nodes metastasis

+

15

0.001

0.156

0.009

0.037–0.608

–

42

Reference