Fig. 4
From: Knockdown of ribosomal protein S15A induces human glioblastoma cell apoptosis
Knockdown of RPS15A induces cell apoptosis via activation of mitochondrial pathway. a Representative images of cell apoptosis of U251 cells with three treatments (shCon, shRPS15A-1, and shRPS15A-2) analyzed by flow cytometry using Annexin V/7-AAD double staining. b Statistical analysis of the proportions of U251 cells corresponding to early (Annexin V+/7-AAD−) and late (Annexin V+/7-AAD+) apoptotic cells. c Activation of bcl-2, caspase-3, and PARP signaling pathways measured by Western blot analysis. The experiment was performed in triplicate and repeated three times. ***p < 0.001