Table 2 Characteristic summary of studies that detected the K-ras gene in plasma
From: Prognostic significance of K-ras mutations in pancreatic cancer: a meta-analysis
Author | Year | Country | Ethnicity | Age (years) | Gender (M/F) | K-ras (mutant/wild) | HR (95 % CI) | Outcome | Sites |
|---|---|---|---|---|---|---|---|---|---|
Kinugasa, H [28] | 2015 | Japan | Asians | 66 (47–85) | 54/21 | 47/28 | 1.84 (1.1–3.25) | OS | 12, 13, 61 |
Castells, A [12] | 1999 | Spain | Caucasian | NR | NR | 12/32 | 1.51 (1.02–2.23) | OS | 12 |
Chen, H.H. [30] | 2010 | China | Asians | 60 (37–78) | 57/34 | 30/61 | 7.39 (3.7–14.9) | OS | 12 |
Yadama, T [31] | 1998 | Japan | Asians | 63.9 (35–78) | 11/4 | 11/4 | 4.7 (2.8–21.2) | OS | 12 |
Combined | 2.23 (1.69–2.95) | OS |