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Table 5 Univariate and multivariate analyses of potential risk factors for overall survival in patients with invasive cancer (n = 272)

From: Comparison of ipsilateral breast tumor recurrence after breast-conserving surgery between ductal carcinoma in situ and invasive breast cancer

Variables

Univariate

Multivariate

HR (95 % CI)

p value

HR (95 % CI)

p value

Age <40 years

0.6 (0.2–2.4)

0.51

1.2 (1.5–9.7)

0.88

T stage, T2 (vs. T1)

1.8 (0.9–3.2)

0.12

2.1 (0.3–5.7)

0.54

Positive LN

3.6 (1.5–11.3)

0.02*

6.9 (1.2–38.4)

0.03*

Stage, IIB-IIIA

4.8 (1.2–19.6)

0.03*

4.9 (1.6–29.3)

0.02*

IBTR

21.9 (4.7–101.9)

<0.001*

31.8 (6.1–165.3)

<0.001*

Positive margin status

1

0.85

1

0.93

Omission of Radiotherapy

1

0.78

1

0.92

Negative ER

1.6 (0.5–4.4)

0.40

3.1 (0.7–12.3)

0.12

Negative PR

1.8 (0.7–4.9)

0.26

3.4 (0.8–14.3)

0.09

Positive HER2

1.2 (0.1–8.3)

0.92

1

0.95

Positive LVI

1.2 (0.2–1.3)

0.84

2.3 (0.3–18.8)

0.43

Positive Ki-67

1.1 (0.4–2.9)

0.87

1.5 (0.3–5.9)

0.64

High histologic grade

1

0.84

1

0.97

  1. *p < 0.05