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Table 5 Univariate and multivariate analyses of potential risk factors for overall survival in patients with invasive cancer (n = 272)

From: Comparison of ipsilateral breast tumor recurrence after breast-conserving surgery between ductal carcinoma in situ and invasive breast cancer

Variables Univariate Multivariate
HR (95 % CI) p value HR (95 % CI) p value
Age <40 years 0.6 (0.2–2.4) 0.51 1.2 (1.5–9.7) 0.88
T stage, T2 (vs. T1) 1.8 (0.9–3.2) 0.12 2.1 (0.3–5.7) 0.54
Positive LN 3.6 (1.5–11.3) 0.02* 6.9 (1.2–38.4) 0.03*
Stage, IIB-IIIA 4.8 (1.2–19.6) 0.03* 4.9 (1.6–29.3) 0.02*
IBTR 21.9 (4.7–101.9) <0.001* 31.8 (6.1–165.3) <0.001*
Positive margin status 1 0.85 1 0.93
Omission of Radiotherapy 1 0.78 1 0.92
Negative ER 1.6 (0.5–4.4) 0.40 3.1 (0.7–12.3) 0.12
Negative PR 1.8 (0.7–4.9) 0.26 3.4 (0.8–14.3) 0.09
Positive HER2 1.2 (0.1–8.3) 0.92 1 0.95
Positive LVI 1.2 (0.2–1.3) 0.84 2.3 (0.3–18.8) 0.43
Positive Ki-67 1.1 (0.4–2.9) 0.87 1.5 (0.3–5.9) 0.64
High histologic grade 1 0.84 1 0.97
  1. *p < 0.05