Table 3 Univariate and multivariate analyses of predictive risk factors for IBTR in invasive cancer (n = 272)
Variables | Univariate | Multivariate | ||
|---|---|---|---|---|
OR (95 % CI) | p value | HR (95 % CI) | p value | |
Age <40 years | 1.3 (0.8–6.7) | 0.06 | 2.9 (0.9–9.2) | 0.07 |
Tumor size >2 cm | 1.1 (0.5–2.1) | 0.85 | 0.9 (0.5–1.9) | 0.94 |
Positive margin status | 1 | 0.99 | 1 | 0.99 |
Multiplicity | 0.78 (0.1–6.3) | 0.82 | 1.2 (0.2–9.8) | 0.81 |
High nuclear grade | 1 | 0.99 | 2.5 (0.8–7.6) | 0.86 |
EIC positive | 1.5 (0.3–6.9) | 0.59 | 1.4 (0.3–6.7) | 0.08 |
Negative ER | 7.9 (2.4–26.1) | 0.001* | 7.5 (2.3–23.8) | 0.001* |
Negative PR | 8.2 (2.2–30.0) | 0.002* | 7.7 (2.2–27.8) | 0.002* |
Positive HER2 | 2.0 (0.3–16.1) | 0.50 | 1.1 (0.7–17.3) | 0.95 |
Positive LVI | 1.4 (0.2–10.8) | 0.77 | 1.3 (0.3–11.2) | 0.72 |
Positive Ki-67 | 4.8 (1.1–21.7) | 0.04* | 5.0 (1.0–20.8) | 0.04* |
Omission of Radiotherapy | 5.6 (0.3–17.2) | 0.03* | 50.0 (12.8–194.5) | <0.001* |