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Table 3 Hazard of recurrence in association with multiple factors

From: Surgery methods and soft tissue extension are the potential risk factors of local recurrence in giant cell tumor of bone

Parameter Hazard 95 % CI P value
Gender    
 Male 0.921 0.469–1.807 0.810
 Female 1.000   
Age    
 ≤30 1.595 0.800–3.178 0.185
 >30 1.000   
Location    
 Distal femur 2.242 0.630–7.791 0.212
 Proximal tibia 0.659 0.129–3.361 0.616
 Distal radius 2.049 0.284–14.766 0.477
 Proximal femur 2.090 0.332–13.157 0.432
 Proximal humerus 2.186 0.356–13.420 0.398
 Distal tibia 2.736 0.593–12.867 0.195
 Proximal fibula 3.325 0.501–22.073 0.213
 Sacrum 0.411 0.058–2.903 0.373
 Others 1.000   2.2
Campanacci grade    
 I 2.199 0.234–20.672 0.491
 II 3.000 0.405–22.196 0.282
 III 1.000   
Soft tissue extension    
 With extension 7.921 1.107–56.671 0.039
 Without extension 1.000   
Pathological fracture    
 With fracture 1.336 0.507–3.517 0.558
 Without fracture 1.000   
Treatments    
 Wide resection 0.044 0.011–0.175 0.000
 Extension curettage    
  Abrasion + bone grafting 0.144 0.044–0.471 0.001
  Abrasion + PMMA 0.113 0.034–0.375 0.000
 Curettage    
  Alcohol 0.410 0.100–1.682 0.216
  Iodine tincture or H2O2 1.000   
  1. PMMA polymethylmethacrylate, H 2 O 2 hydrogen peroxide, CI confidence interval