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Table 3 Hazard of recurrence in association with multiple factors

From: Surgery methods and soft tissue extension are the potential risk factors of local recurrence in giant cell tumor of bone

Parameter

Hazard

95 % CI

P value

Gender

   

 Male

0.921

0.469–1.807

0.810

 Female

1.000

  

Age

   

 ≤30

1.595

0.800–3.178

0.185

 >30

1.000

  

Location

   

 Distal femur

2.242

0.630–7.791

0.212

 Proximal tibia

0.659

0.129–3.361

0.616

 Distal radius

2.049

0.284–14.766

0.477

 Proximal femur

2.090

0.332–13.157

0.432

 Proximal humerus

2.186

0.356–13.420

0.398

 Distal tibia

2.736

0.593–12.867

0.195

 Proximal fibula

3.325

0.501–22.073

0.213

 Sacrum

0.411

0.058–2.903

0.373

 Others

1.000

 

2.2

Campanacci grade

   

 I

2.199

0.234–20.672

0.491

 II

3.000

0.405–22.196

0.282

 III

1.000

  

Soft tissue extension

   

 With extension

7.921

1.107–56.671

0.039

 Without extension

1.000

  

Pathological fracture

   

 With fracture

1.336

0.507–3.517

0.558

 Without fracture

1.000

  

Treatments

   

 Wide resection

0.044

0.011–0.175

0.000

 Extension curettage

   

  Abrasion + bone grafting

0.144

0.044–0.471

0.001

  Abrasion + PMMA

0.113

0.034–0.375

0.000

 Curettage

   

  Alcohol

0.410

0.100–1.682

0.216

  Iodine tincture or H2O2

1.000

  
  1. PMMA polymethylmethacrylate, H 2 O 2 hydrogen peroxide, CI confidence interval