Table 1 Patient and tumor characteristics
Surgery only | Adjuvant CT | p value | |
|---|---|---|---|
N = 187 | N = 430 | ||
Sex | 0.911 | ||
M | 127 (67.9) | 294 (68.4) | |
F | 60 (32.1) | 136 (31.6) | |
Age (median, years) | 0.015 | ||
70 (31~96) | 66 (29~90) | ||
<65 | 58 (31.0) | 193 (45.0) | 0.001 |
≥65 | 129 (69.0) | 236 (55.0) | |
Performance status (ECOG) | 0.387 | ||
0 | 181 (96.8) | 422 (98.1) | |
1 | 4 (2.1) | 6 (1.4) | |
2 | 1 (0.5) | 2 (0.5) | |
3 | 1 (0.5) | 0 | |
Preoperative CEA (ng/mL) | 2.2 (0.2~98.8) | 2.4 (0.2~169.1) | 0.710 |
Scope of LN dissection | 0.004 | ||
D1 | 23 (12.5) | 31 (7.2) | |
D1 + A | 1 (0.5) | 23 (5.4) | |
D1 + B | 5 (2.7) | 23 (5.4) | |
D2 | 151 (82.1) | 347 (81.1) | |
D3 | 4 (2.2) | 4 (0.9) | |
Histology | 0.209 | ||
Differentiated | 88 (47.1) | 226 (52.6) | |
Undifferentiated | 99 (52.9) | 204 (47.4) | |
Lymphatic invasion | 0.948 | ||
No | 60 (32.1) | 136 (31.6) | |
Yes | 127 (67.9) | 293 (68.1) | |
Unknown | 0 | 1 (0.2) | |
Depth of tumor invasion (AJCC 7th) | |||
T stage | 0.073 | ||
T1a | 3 (1.6) | 3 (0.7) | |
T2 | 26 (13.9) | 69 (16.05) | |
T3 | 91 (48.7) | 165 (38.4) | |
T4a | 58 (31.0) | 160 (37.2) | |
T4b | 8 (4.3) | 24 (5.6) | |
N stage | <0.001 | ||
N0 | 55 (29.4) | 70 (16.28) | |
N1 | 48 (25.7) | 104 (24.19) | |
N2 | 48 (25.7) | 108 (25.12) | |
N3a | 25 (13.4) | 88 (20.47) | |
N3b | 11 (5.9) | 60 (13.95) | |
Stage | 0.002 | ||
IIA | 74 (39.6) | 102 (23.72) | |
IIB | 35 (18.7) | 89 (20.7) | |
IIIA | 27 (14.4) | 67 (15.58) | |
IIIB | 24 (12.8) | 92 (21.39) | |
IIIC | 27 (14.4) | 78 (18.60) |