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Table 5 Baseline clinicopathologic characteristics and their association with OS in univariate analysis

From: Two cases of gallbladder metastasis from renal cell carcinoma and review of literature

Parameters No. of patients (%) HR (95 % CI) p value No. of patients available for analysis
Sex 37/52
 Male 25 (67.6) 1 (referent)   
 Female 12 (32.4) 1.37 (0.30–6.25) 0.682  
Age 37/52
 >45 33 (89.2) 1 (referent)   
 <45 4 (10.8) 8.98 (1.78–45.18) 0.008  
Presentation 28/42
 Asymptomatic 7 (25) 1 (referent)   
 Symptomatic 21 (75) 2.97 (0.59–14.77) 0.183  
Timing 37/52
 Synchronousa 14 (37.8) 1 (referent)   
 Metachronous 23 (62.2) 3.25 (0.39–27.10) 0.276  
Staging 28/52
 1 2 (7.1) b   
 2 4 (14.3) 1 (referent)   
 3 5 (17.9) 0.56 (0.05–6.33)   
 4 17 (60.7) 0.74 (0.30–1.83) 0.676  
Single vs. multiple 36/52
 Single 20 (55.6) 1 (referent)   
 Multiple 16 (44.4) 2.77 (0.50–15.28) 0.241  
Interval from resection of primary to diagnosis of metastasis 23/35c
 >24 months 17 (73.9) 1 (referent)   
 <24 months 6 (26.1) 10.80 (1.07–108.34) 0.043  
Adjuvant chemotherapy  
 Yes 6 (28.6) 1 (referent)   21/52
 No 15 (71.4) 2.28 (0.25–20.58) 0.461  
  1. Abbreviations: HR hazards ratio, CI confidence interval
  2. aDiagnosis at the time of diagnosis of primary tumour
  3. bAll cases are censored
  4. cOnly
  5. Statistically significant pvalue is highlighted in italic