Table 5 Baseline clinicopathologic characteristics and their association with OS in univariate analysis
From: Two cases of gallbladder metastasis from renal cell carcinoma and review of literature
Parameters | No. of patients (%) | HR (95 % CI) | p value | No. of patients available for analysis |
|---|---|---|---|---|
Sex | 37/52 | |||
Male | 25 (67.6) | 1 (referent) | ||
Female | 12 (32.4) | 1.37 (0.30–6.25) | 0.682 | |
Age | 37/52 | |||
>45 | 33 (89.2) | 1 (referent) | ||
<45 | 4 (10.8) | 8.98 (1.78–45.18) | 0.008 | |
Presentation | 28/42 | |||
Asymptomatic | 7 (25) | 1 (referent) | ||
Symptomatic | 21 (75) | 2.97 (0.59–14.77) | 0.183 | |
Timing | 37/52 | |||
Synchronousa | 14 (37.8) | 1 (referent) | ||
Metachronous | 23 (62.2) | 3.25 (0.39–27.10) | 0.276 | |
Staging | 28/52 | |||
1 | 2 (7.1) | b | ||
2 | 4 (14.3) | 1 (referent) | ||
3 | 5 (17.9) | 0.56 (0.05–6.33) | ||
4 | 17 (60.7) | 0.74 (0.30–1.83) | 0.676 | |
Single vs. multiple | 36/52 | |||
Single | 20 (55.6) | 1 (referent) | ||
Multiple | 16 (44.4) | 2.77 (0.50–15.28) | 0.241 | |
Interval from resection of primary to diagnosis of metastasis | 23/35c | |||
>24 months | 17 (73.9) | 1 (referent) | ||
<24 months | 6 (26.1) | 10.80 (1.07–108.34) | 0.043 | |
Adjuvant chemotherapy | ||||
Yes | 6 (28.6) | 1 (referent) | 21/52 | |
No | 15 (71.4) | 2.28 (0.25–20.58) | 0.461 | |