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Table 1 Characteristics of nine included trials in the meta-analysis

From: Gemcitabine plus cisplatin versus gemcitabine alone in the treatment of pancreatic cancer: a meta-analysis

Studies

Year

Publication type

Inclusion period

Total number

Patients

Median age (range)

Male/female

Jade score

GemCis

Gem

GemCis

Gem

GemCis

Gem

Gem

Colucci

2002

Phase 3

NA

107

53

54

60 (33–71)

63 (43–75)

35:18

27:27

3

Wang

2002

RCT

July 2000 to May 2001

42

22

20

65 (37–76)

57 (35–60)

15:7

14:6

NA

Heinemann

2006

Phase 3

December 1997 to January 2002

190

95

95

66 (37–82)

66 (43–85)

63:33

59:36

4

H. Palmer

2007

Phase 2

November 1999 to May 2003

50

26

24

66 (47–78)

66 (40–79)

13:13

13:11

3

Sun

2007

RCT

January 2003 to February 2006

53

27

26

55

58

17:10

15:11

3

Colucci

2010

Phase 3

April 2004 to April 2007

400

201

199

63 (37–75)

63 (37–75)

125:76

133:86

4

Inal

2012

Retrospective patient series

September 2006 to March 2011

406

250

156

57

63

175:75

98:58

0

Liu

2012

RCT

May 2005 to July 2008

60

30

30

48 (23–74)

45 (20–69)

13:17

14:16

3

Chao

2013

RCT

February 2000 to December 2002

46

21

25

69 (47–81)

69 (46–83)

17:4

18:7

3

  1. NA not available