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Table 3 Outcomes of hepatic resection for patients with BCLC stage B/C HCC in literature review

From: Hepatic resection provided long-term survival for patients with intermediate and advanced-stage resectable hepatocellular carcinoma

Study Patient origins Recruitment period Number HCC characteristics Hospital mortality (%) Median survival (month) Overall survival
1 year 3 years 5 years
Single, large, and/or multinodular HCC
 Cheng et al. [13] Taiwan 1999–2005 104 >5 cm 7.3 90 66
 Heng-Jun et al. [14] China 2000–2009 151 BCLC B 61.8 99 68 52
 Ho et al. [15] Taiwan 1981–2000 294 BCLC B 37.9 77.4 51.9 36.6
 Hsu et al. [16] Taiwan 2002–2010 268 BCLC B+C 2.7 81 63 43
 Jin et al. [17] South Korea 1998–2013 62 BCLC B 11.1 83.2 75.7 65
 Jianyong et al. [18] China 2002–2008 433 BCLC B 2.3 91.8 84.2 70.8
 Lee et al. [19] Korea 1997–2003 100 >10 cm 2.0 66 44 31
 Lim et al. [20] Japan 1994–2010 172 >5 cm 1 58
 Lin et al. [21] Taiwan 2001–2007 93 BCLC B 5.4 29.9 ± 20.1 83 49
 Ng et al. [22] Asia, Europe, USA 1982–2001 380 >5 cm 2.7 74 50 39
 Nojiri et al. [23] Japan 1992–2011 107 >5 cm 62 38.1
 Pandey et al. [24] Singapore 1995–2006 166 >10 cm 3.0 29
 Poon et al. [25] Hong Kong 1991–2000 120 >10 cm 5.0 61 38 28
 Wang et al. [26] Taiwan 1986–2002 243 BCLC B 60.4 ± 6.1 81.5 64.4 50.5
 Yin et al. [27] China 2008–2010 88 BCLC B 11.3 41 76.1 51.5
 Zhong et al. [28] China 2000–2010 660 BCLC B 2.6 91 67 44
 Zhong et al. [29] China 2000–2007 257 BCLC B 3.1 42.9 ± 26.1 84 59 37
Macrovascular invasion HCC
 Chang et al. [30] Taiwan 1991–2006 160 BCLC C 2.7 58 34 29
 Huang et al. [31] China 1998–2008 116 >15 cm 3.4 71 23 11
 Ikai et al. [32] Japan 1992–2003 976 BCLC C 2.5 50 26 18
 Pawlik et al. [33] Asia, Europe, USA 1984–1999 102 BCLC C 5.9 45 17 10
 Shi et al. [34] China 2001–2003 406 BCLC C 0.2 34 13
 Torzilli et al. [35] China, Europe, USA 1990–2009 297 BCLC C 3.0 76 49 38
 Yang et al. [36] China 2001–2007 511 BCLC C 3.0 70 41 31