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Table 2 Univariate and multivariate analysis of prognostic factors for overall survival

From: Extended resection including adjacent organs and Ki-67 labeling index are prognostic factors in patients with retroperitoneal soft tissue sarcomas

Factor

Univariate analysis

Multivariate analysis

HR

95 % CI

P

HR

95 % CI

P

Age (over/under 75 years old)

0.66

0.08–5.24

0.70

   

Symptoms (symptomatic/asymptomatic)

2.44

0.63–9.49

0.20

   

Tumor size (over 10 mm/under 10 mm)

1.49

0.45–4.95

0.52

   

Type of surgery (simple/extended)

4.88

1.21–19.66

*0.026

3.80

1.25–16.59

*0.040

Surgical margins [(R1 + R2)/R0]

3.35

0.42–26.90

0.26

   

Tumor grade [grade 3/(grade 1 + 2)]

1.49

0.31–7.16

0.71

   

Necrosis (presence/absence)

3.05

0.38–24.46

0.29

   

Histologic type (non-liposarcoma/liposarcoma)

3.82

0.98–14.89

0.054

   

Ki-67 LI (≥25 %/<25 %)

4.79

1.25–18.35

*0.022

3.74

1.32–14.94

*0.049

  1. Simple: only tumor resection; extended: resection with adjacent organs
  2. R0 microscopically negative margin, R1 microscopically positive margin, R2 gross residual margin, HR hazard ratio, CI confidence interval, Ki-67 LI Ki-67 labeling index, * = P <0.05