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Table 1 Baseline characteristics of papillary thyroid microcarcinoma patients stratified by the status of metastatic central lymph node

From: A scoring system is an effective tool for predicting central lymph node metastasis in papillary thyroid microcarcinoma: a case-control study

Characteristics Total The status of metastatic central lymph node p value
Positive Negative
Total 498 252 246  
Sex     0.130
 Male (n, %) 143 (28.7 %) 80 (31.7 %) 63 (25.6 %)  
 Female (n, %) 355 (71.3 %) 172 (68.3 %) 183 (74.4 %)  
Age at diagnosis (years)   45.8 ± 9.8 47.2 ± 11.9 0.150
 <45 (n, %) 251 (50.4 %) 136 (54.0 %) 115 (46.7 %) 0.107
 ≥45 (n, %) 247 (49.6 %) 116 (46.0 %) 131 (53.3 %)  
Tumor size (mm)   6.8 ± 2.1 5.7 ± 2.6 <0.001
 ≤5 (n, %) 165 (33.1 %) 51 (20.2 %) 114 (46.3 %) <0.001
 >5 (n, %) 333 (66.9 %) 201 (79.8 %) 132 (53.7 %)  
Tumor location     <0.001
 Lower (n, %) 141 (28.3 %) 93 (36.9 %) 48 (19.5 %)  
 Upper/middle/isthmus (n, %) 357 (71.7 %) 159 (63.1 %) 198 (80.5 %)  
No. of nodules     0.416
 Single (n, %) 431 (86.5 %) 215 (85.3 %) 216 (87.8 %)  
 Multiple (n, %) 67 (13.5 %) 37 (14.7 %) 30 (12.2 %)  
Hashimoto’s thyroiditis     0.348
 Yes (n, %) 87 (17.5 %) 48 (19.0 %) 39 (15.9 %)  
 No (n, %) 411 (82.5 %) 204 (81.0 %) 207 (84.1 %)  
Extrathyroidal extension     <0.001
 Yes (n, %) 249 (50.0 %) 150 (59.5 %) 99 (40.2 %)  
 No (n, %) 249 (50.0 %) 102 (40.5 %) 147 (59.8 %)  
Vascularization     0.29
 Absence (n, %) 435 (87.3 %) 225 (89.3 %) 210 (85.4 %)  
 External vascularization (n, %) 31 (6.2 %) 15 (6.0 %) 16 (6.5 %)  
 Internal vascularization (n, %) 32 (6.4 %) 12 (4.8 %) 20 (8.1 %)  
Intact capsule     0.548
 Yes (n, %) 297 (59.6 %) 147 (58.3 %) 150 (61.0 %)  
 No (n, %) 201 (40.4 %) 105 (41.7 %) 96 (39.0 %)  
Margin     <0.001
 Well-defined (n, %) 246 (89.8 %) 99 (39.3 %) 147 (59.8 %)  
 No well-defined (n, %) 252 (50.6 %) 153 (60.7 %) 99 (40.2 %)  
Shape     0.280
 Regular (n, %) 372 (74.7 %) 183 (72.6 %) 189 (76.8 %)  
 Irregular (n, %) 126 (25.3 %) 69 (27.4 %) 57 (23.2 %)  
Composition     0.188
 Solid (n, %) 435 (87.3 %) 225 (89.3 %) 210 (85.4 %)  
 Cystic or mixed (n, %) 63 (12.7 %) 27 (10.7 %) 36 (14.6 %)  
Calcification     <0.001
 Absence (n, %) 237 (47.6 %) 102 (40.5 %) 135 (54.9 %)  
 Microcalcification (n, %) 207 (41.6 %) 129 (51.2 %) 78 (31.7 %)  
 Other calcification (n, %) 54 (10.8 %) 21 (8.3 %) 33 (13.4 %)  
Taller than wide     0.916
 Yes (n, %) 432 (86.7 %) 219 (86.9 %) 213 (86.6 %)  
 No (n, %) 66 (13.3 %) 33 (13.1 %) 33 (13.4 %)  
Display of enlarged lymph nodes     <0.001
 Yes (n, %) 267 (53.6 %) 165 (65.5 %) 102 (41.5 %)  
 No (n, %) 231 (46.4 %) 87 (34.5 %) 144 (58.5 %)  
Contact of >25 % with the adjacent capsule     <0.001
 Yes (n, %) 153 (30.7 %) 105 (41.7 %) 48 (19.5 %)  
 No (n, %) 345 (69.3 %) 147 (58.3 %) 198 (80.5 %)