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Table 1 Baseline characteristics of papillary thyroid microcarcinoma patients stratified by the status of metastatic central lymph node

From: A scoring system is an effective tool for predicting central lymph node metastasis in papillary thyroid microcarcinoma: a case-control study

Characteristics

Total

The status of metastatic central lymph node

p value

Positive

Negative

Total

498

252

246

 

Sex

   

0.130

 Male (n, %)

143 (28.7 %)

80 (31.7 %)

63 (25.6 %)

 

 Female (n, %)

355 (71.3 %)

172 (68.3 %)

183 (74.4 %)

 

Age at diagnosis (years)

 

45.8 ± 9.8

47.2 ± 11.9

0.150

 <45 (n, %)

251 (50.4 %)

136 (54.0 %)

115 (46.7 %)

0.107

 ≥45 (n, %)

247 (49.6 %)

116 (46.0 %)

131 (53.3 %)

 

Tumor size (mm)

 

6.8 ± 2.1

5.7 ± 2.6

<0.001

 ≤5 (n, %)

165 (33.1 %)

51 (20.2 %)

114 (46.3 %)

<0.001

 >5 (n, %)

333 (66.9 %)

201 (79.8 %)

132 (53.7 %)

 

Tumor location

   

<0.001

 Lower (n, %)

141 (28.3 %)

93 (36.9 %)

48 (19.5 %)

 

 Upper/middle/isthmus (n, %)

357 (71.7 %)

159 (63.1 %)

198 (80.5 %)

 

No. of nodules

   

0.416

 Single (n, %)

431 (86.5 %)

215 (85.3 %)

216 (87.8 %)

 

 Multiple (n, %)

67 (13.5 %)

37 (14.7 %)

30 (12.2 %)

 

Hashimoto’s thyroiditis

   

0.348

 Yes (n, %)

87 (17.5 %)

48 (19.0 %)

39 (15.9 %)

 

 No (n, %)

411 (82.5 %)

204 (81.0 %)

207 (84.1 %)

 

Extrathyroidal extension

   

<0.001

 Yes (n, %)

249 (50.0 %)

150 (59.5 %)

99 (40.2 %)

 

 No (n, %)

249 (50.0 %)

102 (40.5 %)

147 (59.8 %)

 

Vascularization

   

0.29

 Absence (n, %)

435 (87.3 %)

225 (89.3 %)

210 (85.4 %)

 

 External vascularization (n, %)

31 (6.2 %)

15 (6.0 %)

16 (6.5 %)

 

 Internal vascularization (n, %)

32 (6.4 %)

12 (4.8 %)

20 (8.1 %)

 

Intact capsule

   

0.548

 Yes (n, %)

297 (59.6 %)

147 (58.3 %)

150 (61.0 %)

 

 No (n, %)

201 (40.4 %)

105 (41.7 %)

96 (39.0 %)

 

Margin

   

<0.001

 Well-defined (n, %)

246 (89.8 %)

99 (39.3 %)

147 (59.8 %)

 

 No well-defined (n, %)

252 (50.6 %)

153 (60.7 %)

99 (40.2 %)

 

Shape

   

0.280

 Regular (n, %)

372 (74.7 %)

183 (72.6 %)

189 (76.8 %)

 

 Irregular (n, %)

126 (25.3 %)

69 (27.4 %)

57 (23.2 %)

 

Composition

   

0.188

 Solid (n, %)

435 (87.3 %)

225 (89.3 %)

210 (85.4 %)

 

 Cystic or mixed (n, %)

63 (12.7 %)

27 (10.7 %)

36 (14.6 %)

 

Calcification

   

<0.001

 Absence (n, %)

237 (47.6 %)

102 (40.5 %)

135 (54.9 %)

 

 Microcalcification (n, %)

207 (41.6 %)

129 (51.2 %)

78 (31.7 %)

 

 Other calcification (n, %)

54 (10.8 %)

21 (8.3 %)

33 (13.4 %)

 

Taller than wide

   

0.916

 Yes (n, %)

432 (86.7 %)

219 (86.9 %)

213 (86.6 %)

 

 No (n, %)

66 (13.3 %)

33 (13.1 %)

33 (13.4 %)

 

Display of enlarged lymph nodes

   

<0.001

 Yes (n, %)

267 (53.6 %)

165 (65.5 %)

102 (41.5 %)

 

 No (n, %)

231 (46.4 %)

87 (34.5 %)

144 (58.5 %)

 

Contact of >25 % with the adjacent capsule

   

<0.001

 Yes (n, %)

153 (30.7 %)

105 (41.7 %)

48 (19.5 %)

 

 No (n, %)

345 (69.3 %)

147 (58.3 %)

198 (80.5 %)