Table 1 Characteristics of all surgical patients
Variable | Synchronous disease (n = 34) | Metachronous disease (n = 38) | Conversion disease (n = 16) | p | |
|---|---|---|---|---|---|
Age, yearsa | 67.5 (35–85) | 63 (35–88) | 57.5 (32–80) | 0.0458 | |
Sex, n (%) | |||||
Male | 22 (64.7 %) | 20 (52.6 %) | 8 (50 %) | 0.487 | |
Female | 12 (35.3 %) | 18 (47.4 %) | 8 (50 %) | ||
T, n (%) | |||||
T1/2 | 1 (2.9 %) | 3 (7.9 %) | 0 (0 %) | 0.377 | |
T3/4 | 33 (97.1 %) | 35 (92.1 %) | 16 (100 %) | ||
N, n (%) | |||||
N− | 13 (38.2 %) | 19 (50 %) | 7 (43.8 %) | 0.603 | |
N+ | 21 (61.8 %) | 19 (50 %) | 9 (56.3 %) | ||
Location of primary tumor, n (%) | |||||
Colon | 22 (64.7 %) | 23 (60.5 %) | 12 (75 %) | 0.596 | |
Rectum | 12 (35.3 %) | 15 (39.5 %) | 4 (25 %) | ||
Preoperative chemotherapy, n (%) | |||||
Yes | 5 (14.7 %) | 10 (26.3 %) | 16 (100 %) | <0.0001 | |
No | 29 (85.3 %) | 28 (73.7 %) | 0 (0 %) | ||
Adjuvant chemotherapy, n (%) | |||||
Yes | 16 (47.1 %) | 7 (18.4 %) | 7 (43.8 %) | 0.0252 | |
No | 18 (52.9 %) | 31 (81.6 %) | 9 (56.3 %) | ||
No. of liver metastases, n (%) | |||||
1 | 10 (29.4 %) | 22 (57.9 %) | 1 (6.3 %) | <0.0001 | |
2–4 | 15 (44.1 %) | 10 (26.3 %) | 2 (12.5 %) | ||
≥5 | 9 (26.5 %) | 6 (15.8 %) | 13 (81.3 %) | ||
Size, n (%) | |||||
0–5 cm | 28 (82.4 %) | 35 (92.1 %) | 11 (68.8 %) | 0.0946 | |
>5 cm | 6 (17.6 %) | 3 (7.9 %) | 5 (31.3 %) | ||
Resection, n (%) | |||||
0 | 31 (81.6 %) | 38 (100 %) | 9 (56.3 %) | <0.0001 | |
1 | 3 (18.4 %) | 0 (0 %) | 7 (43.8 %) | ||
CEA (ng/mL)a | 17.9 (2.1–2300) | 12.45 (1.6–196.3) | 11.35 (2.4–7510) | 0.729 | |
CA19-9 (U/mL)a | 19.45 (2–7676) | 19.8 (2–7191) | 27.3 (2–1063) | 0.78 |