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Table 4 Independent prognostic factors for overall survival (univariate analysis)

From: Emergency endoscopic variceal ligation following variceal rupture in patients with advanced hepatocellular carcinoma and portal vein tumor thrombosis: a retrospective study

Variable

Hazard ratio

95 % CI

p value

Age <62 years

0.752

0.448–1.263

0.2813

Sex (female)

0.794

0.412–1.529

0.4895

HBV

0.859

0.402–1.836

0.6956

HCV

1.509

0.727–3.131

0.2698

Ascites (−)

0.923

0.408–1.747

0.8058

Encephalopathy (−)

0.532

0.289–1.135

0.1425

Albumin <2.9 g/dL

1.084

0.651–1.805

0.7565

Total bilirubin <1.4 mg/dL

0.601

0.359–1.007

0.0533

Prothrombin time <68 %

1.882

1.125–3.150

0.0161

Platelet count <12.0 × 104/mm3

0.692

0.413–1.158

0.1618

AST <117 IU/L

0.631

0.374–1.063

0.0834

ALT <48.5 IU/L

0.744

0.442–1.253

0.2664

Child-Pugh class A/B

0.350

0.179–0.554

<0.0001

Tumor size (<6.8 cm)

0.696

0.416–1.163

0.1540

Tumor number (multiple)

2.296

0.903–5.842

0.0810

Extrahepatic metastasis (−)

0.800

0.455–1.407

0.4385

PVTT (without main trunk)

1.284

0.762–2.162

0.3467

AFP <100 ng/dL

0.619

0.352–1.088

0.0958

AFP-L3 < 37.4 %

0.452

0.252–0.813

0.0080

DCP <100 ng/dL

0.481

0.189–1.220

0.1233

Variceal rupture (esophagus)

1.209

0.435–3.344

0.7193

EVL (−)

2.031

0.279–14.802

0.4844

Rebleeding (−)

1.091

0.651–1.826

0.7415

  1. AFP α-fetoprotein, AFP-L3 lectin-reactive α-fetoprotein, ALT aspartate aminotransferase, AST alanine aminotransferase, CI confidence interval, DCP des-gamma carboxyprothrombin, EVL endoscopic variceal band ligation, HBV hepatitis B virus, HCV hepatitis C virus, PVTT portal vein tumor thrombus