Emergency endoscopic variceal ligation following variceal rupture in patients with advanced hepatocellular carcinoma and portal vein tumor thrombosis: a retrospective study

Table 3 Significant predictors for rebleeding-free survival

Variable	Hazard ratio	95 % CI	p value
Age >62 years	0.466	0.165–1.318	0.1500
Sex (male)	1.129	0.292–4.360	0.8602
HCV	1.046	0.338–3.238	0.9382
NBNC	1.778	0.403–7.845	0.4474
Ascites (+)	1.333	0.354–5.026	0.6709
Encephalopathy (+)	1.780	0.382–7.559	0.4857
Albumin >2.9 g/dL	0.714	0.255–2.003	0.5224
Total bilirubin >1.4 mg/dL	0.436	0.153–1.244	0.1208
Prothrombin time >68 %	1.729	0.615–4.860	0.2987
Platelet count >12.0 × 10⁴/mm³	2.147	0.759–6.074	0.1500
AST >117 IU/L	0.643	0.229–1.804	0.4012
ALT >48.5 IU/L	1.729	0.615–4.860	0.2987
Child-Pugh class C	0.458	0.149–1.414	0.1746
Tumor size (>6.8 cm)	1.438	0.86–2.403	0.166
Tumor number (single)	0.287	0.031–2.662	0.2687
Extrahepatic metastasis (+)	1.153	0.369–3.600	0.8064
PVTT (main trunk)	3.706	1.205–11.401	0.0223
AFP >100 ng/dL	0.714	0.234–2.177	0.5540
AFP-L3 > 37.4 %	1.385	0.439–4.372	0.5790
DCP >100 ng/dL	3.485	0.381–31.839	0.2687
Variceal rupture (stomach)	5.286	0.516–54.103	0.1606

AFP alpha-fetoprotein, AFP-L3 lectin-reactive alpha-fetoprotein, ALT aspartate aminotransferase, AST alanine aminotransferase, CI confidence interval, DCP des-gamma carboxyprothrombin, HCV hepatitis C virus, NBNC non-B non-C hepatitis, PVTT portal vein tumor thrombus

ISSN: 1477-7819