From: TNRC9 rs12443621 and FGFR2 rs2981582 polymorphisms and breast cancer risk
SNP | Genotypes | Cases | Controls | χ 2a | P a | ORa | 95 % CIa | Adjusted ORb | 95 % CIb |
---|---|---|---|---|---|---|---|---|---|
TNRC9 | AA | 10 (11.2) | 79 (18.8) | 8.100 | 0.017 | 1.0 | 1.0 | ||
rs12443621 | AG | 24 (22.86) | 94 (24.61) | 2.017 | 0.910–4.471 | 0.621 | 0.075–5.129 | ||
GG | 71 (67.62) | 209 (54.71) | 2.684 | 1.318–5.463 | 1.569 | 0.233–10.556 | |||
AG + GG | 95 (90.48) | 303 (79.32) | |||||||
G allele | 0.79 | 0.670 | |||||||
FGFR2 | GG | 50 (47.62) | 120 (31.41) | 10.203 | 0.006 | 1.0 | 1.0 | ||
rs2981582 | GA | 27 (25.71) | 146 (38.22) | 0.444 | 0.262–0.752 | 0.557 | 0.141–2.199 | ||
AA | 28 (26.67) | 116 (30.37) | 0.579 | 0.342–0.983 | 0.559 | 0.154–2.032 | |||
GA + AA | 55 (52.38) | 262 (68.59) | |||||||
A allele | 0.395 | 0.495 | |||||||
TNRC9 | CC | 76 (72.38) | 250 (65.44) | 1.791 | 0.408 | 1.0 | 1.0 | ||
rs3803662 | CT | 21 (20) | 96 (25.13) | 0.720 | 0.420–1.232 | 0.304 | 0.075–1.241 | ||
TT | 8 (7.61) | 36 (9.42) | 0.731 | 0.326–1.640 | 0.008 | 0.001–0.01 | |||
CT + TT | 29 (27.62) | 132 (34.56) | |||||||
T allele | 0.176 | 0.219 | |||||||
LSP1 | TT | 85 (80.95) | 272 (71.20) | 4.310 | 0.116 | 1.0 | 1.0 | ||
rs3817198 | TC | 18 (17.14) | 93 (24.35) | 0.619 | 0.354–1.085 | 0.059 | 0.159–2.183 | ||
CC | 2 (1.90) | 17 (4.45) | 0.376 | 0.085–1.663 | 0.00 | 0.00–0.00 | |||
TC + CC | 20 (19.05) | 110 (28.80) | |||||||
C allele | 0.104 | 0.166 |