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Table 2 Meta-analysis of HER2 amplification in patients with pancreatic cancer

From: Prognostic role of HER2 amplification based on fluorescence in situ hybridization (FISH) in pancreatic ductal adenocarcinoma (PDAC): a meta-analysis

Clinicopathological parameters

No. of studies

Cases

Model

OR

95 % CI

P value for OR

P value for heterogeneity

Age (≤60/>60)

3

172

R

0.71

0.10–5.21

0.74

0.12

Gender (male/female)

5

691

F

1.25

0.66–2.36

0.49

0.60

Location (head/other)

2

556

R

7.58

0.60–95.35

0.12

0.08

Differentiation (well + moderate/poorly)

6

726

F

0.81

0.42–1.60

0.55

0.33

Lymph node metastasis (yes/no)

4

696

F

1.10

0.59–2.07

0.76

0.96

T stage (T1 + T2/T3 + T4)

2

86

F

0.74

0.34–1.62

0.16

0.45

TNM (I + II/III + IV)

4

645

R

0.87

0.14–5.63

0.89

0.04

  1. OR odds ratio, CI confidence interval, F fixed-effect model, R random-effect model