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Table 2 Pathologic characteristics of patients with stage I pulmonary adenocarcinoma according to lepidic component

From: The importance of the lepidic component as a prognostic factor in stage I pulmonary adenocarcinoma

 

Group 1

Group 2

Group 3

p value

Tumor size, cm (±SD)

2.2 (±0.9) cm

2.3 (±0.9) cm

2.0 (±0.7) cm

0.076

Pleural invasion, n (%)

23 (31.9 %)

18 (24.3 %)

4 (7.5 %)

0.005

Lymphatic invasion, n (%)

21 (29.2 %)

28 (37.8 %)

9 (17.0 %)

0.039

Vascular invasion, n (%)

9 (12.5 %)

9 (12.5 %)

1 (1.9 %)

0.088

Differentiation

   

<0.001

 Mild, n (%)

15 (20.5 %)

41 (54.7 %)

48 (90.6 %)

 

 Moderate, n (%)

49 (67.1 %)

31 (41.3 %)

5 (9.4 %)

 

 Poor, n (%)

9 (12.3 %)

3 (4.0 %)

0 (0 %)

 

EGFR mutation

75.4 %

90.3 %

79.4 %

0.087

Micropapillary component, % (±SD)

3.4 (±9.4)%

3.0 (±8.5)%

0.1 (±0.7)%

0.006

Solid component, % (±SD)

15.2 (±27.9)%

1.1 (±3.7)%

0.3 (±1.6)%

<0.001

Acinar component, % (±SD)

49.0 (±37.7)%

52.2 (±21.6)%

21.0 (±11.2)%

<0.001

Papillary component, % (±SD)

23.8 (±22.5)%

8.7 (±18.2)%

2.9 (±6.8)%

<0.001

  1. Group 1 = lepidic component ≤10 %; group 2 = lepidic component >10 to 50 %; group 3 = lepidic component >50 %
  2. EGFR epidermal growth factor receptor, SD standard deviation