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Table 1 Clinical characteristics of patients with pulmonary adenocarcinoma, according to disease stage and lepidic component

From: The importance of the lepidic component as a prognostic factor in stage I pulmonary adenocarcinoma

 

Stage I

Stage IIA

p valueb

Total

Group 1

Group 2

Group 3

p valuea

(n = 23)

(n = 217)

(n = 73)

(n = 75)

(n = 53)

 

Age, years (±SD)

64.0 (±9.3)

64.5 (±10.3)

65.2 (±9.4)

61.8 (±7.4)

0.121

61.0 (±7.5)

0.131

Sex

    

<0.001

 

0.518

 Female, n (%)

117 (58.2 %)

29 (39.7 %)

59(78.7 %)

29(54.7 %)

 

15 (65.2)

 

 Male, n (%)

84 (41.8 %)

44 (60.3 %)

16 (21.3 %)

24 (45.3 %)

 

8 (34.8)

 

Smoking, pack years (±SD)

8.6 (±15.6)

14.2 (±19.1)

3.8 (±10.9)

7.3 (±13.3)

<0.001

5.7 (±14.7)

0.424

Laterality

    

0.469

 

0.038

 Right, n (%)

137 (68.2 %)

47 (64.4 %)

55 (73.3 %)

35 (66.0 %)

 

10 (43.5 %)

 

 Left, n (%)

64 (31.8 %)

26 (35.6 %)

20 (26.7 %)

18 (34.0 %)

 

13 (56.5 %)

 

SUVmax (±SD)

3.6 (±3.2)

4.5 (±3.8)

3.7 (±3.0)

2.0 (±1.8)

<0.001

8.8 (±3.7)

<0.001

Extent of operation

    

0.416

 

0.273

 Wedge resection, n (%)

17 (8.5 %)

8 (11.0 %)

5 (6.7 %)

4 (7.5 %)

 

0

 

 Segmentectomy, n (%)

10 (5.0 %)

2 (2.7 %)

6 (8.0 %)

2 (3.8 %)

 

0

 

 Lobectomy, n (%)

170 (84.6 %)

62 (84.9 %)

61 (81.3 %)

47 (88.7 %)

 

22 (95.7 %)

 

 Bilobectomy, n (%)

4 (2.0 %)

1 (1.4 %)

3 (4.0 %)

0

 

1 (4.3 %)

 

Surgical approach

    

0.475

 

0.692

 VATS, n (%)

178 (88.6 %)

62 (84.9 %)

68 (90.7 %)

48 (90.6 %)

 

21 (91.3 %)

 

 Thoracotomy, n (%)

21 (11.4 %)

11 (15.1 %)

7 (9.3 %)

5 (9.4 %)

 

2 (8.7 %)

 

Sampled lymph node, n (±SD)

13.5 (±9.5)

14.0 (±10.7)

14.0 (±9.2)

12.3(±7.9)

0.537

17.7 (±8.5)

0.043

  1. Group 1 = lepidic component ≤10 %; group 2 = lepidic component >10 to 50 %; group 3 = lepidic component >50 %
  2. SD standard deviation, SUVmax maximum standardized uptake value of fluorodeoxyglucose, VATS video-assisted thoracoscopic surgery
  3. aComparison among groups 1, 2, and 3
  4. bComparison between stage I and stage IIA