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Table 2 CDK5 expression in lung cancer compared with normal lung tissue

From: An immunohistochemical study of cyclin-dependent kinase 5 (CDK5) expression in non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC): a possible prognostic biomarker

Cancer and normal lung tissue n CDK5 negative (n, %) CDK5 positive (n, %) Z P
Normal lung tissue 30 24(80.0) 6(20.0)   
Cancer tissue 365 177(48.5) 188(51.5) −3.314 0.001
 SCLC    26 11(42.3) 15(57.7) −2.880 0.004
 NSCLC    339 166(49.0) 173(51.0) −3.225 0.001
  Squamous cell carcinoma   175 88(50.3) 87(49.7) −3.013 0.003
  Adenosquamous carcinoma   28 10(35.7) 18(64.3) −3.392 0.001
  Undifferentiated carcinoma   8 3(37.5) 5(62.5) −2.324 0.020
  Large cell carcinoma   1 1(100) 0(0) −0.490 0.624
  Adenocarcinoma   127 64(50.4) 63(49.6) −2.929 0.003
   Acinar adenocarcinoma 83 36(43.4) 47(56.6) −3.430 0.001
   Papillary adenocarcinoma 19 12(63.2) 7(36.8) −1.288 0.198
   Bronchioloalveolar cell carcinoma 18 10(55.6) 8(44.4) −1.785 0.074
   Mucinous carcinoma 7 6(85.7) 1(14.3) −0.343 0.732
  1. Non-small cell lung cancer (NSCLC) vs small cell lung cancer (SCLC) P = 0.513