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Table 2 CDK5 expression in lung cancer compared with normal lung tissue

From: An immunohistochemical study of cyclin-dependent kinase 5 (CDK5) expression in non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC): a possible prognostic biomarker

Cancer and normal lung tissue

n

CDK5 negative (n, %)

CDK5 positive (n, %)

Z

P

Normal lung tissue

30

24(80.0)

6(20.0)

  

Cancer tissue

365

177(48.5)

188(51.5)

−3.314

0.001

 SCLC

  

26

11(42.3)

15(57.7)

−2.880

0.004

 NSCLC

  

339

166(49.0)

173(51.0)

−3.225

0.001

 

Squamous cell carcinoma

 

175

88(50.3)

87(49.7)

−3.013

0.003

 

Adenosquamous carcinoma

 

28

10(35.7)

18(64.3)

−3.392

0.001

 

Undifferentiated carcinoma

 

8

3(37.5)

5(62.5)

−2.324

0.020

 

Large cell carcinoma

 

1

1(100)

0(0)

−0.490

0.624

 

Adenocarcinoma

 

127

64(50.4)

63(49.6)

−2.929

0.003

  

Acinar adenocarcinoma

83

36(43.4)

47(56.6)

−3.430

0.001

  

Papillary adenocarcinoma

19

12(63.2)

7(36.8)

−1.288

0.198

  

Bronchioloalveolar cell carcinoma

18

10(55.6)

8(44.4)

−1.785

0.074

  

Mucinous carcinoma

7

6(85.7)

1(14.3)

−0.343

0.732

  1. Non-small cell lung cancer (NSCLC) vs small cell lung cancer (SCLC) P = 0.513