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Table 2 Meta-analysis of the impact of obesity on outcomes after rectal cancer surgery

From: Outcome of rectal cancer surgery in obese and nonobese patients: a meta-analysis

Outcome of interest No. of studies Events OR/WMD 95 % CI P value I 2 (%)
Obese (%) Nonobese (%)
Operative outcomes
Conversion rates 4 [6, 7, 13, 16] 26/92 (28.3 %) 100/734 (13.6 %) 2.78 1.67, 4.61 <0.001 41.3
Postoperative outcomes
Overall morbidity 7 [6, 7, 12, 13, 1517] 1320/3259 (40.5 %) 3264/9911 (32.9 %) 1.36 1.25, 1.47 <0.001 0
Mortality 8 [6, 7, 1114, 16, 17] 34/3472 (1.0 %) 109/10,329 (1.0 %) 0.95 0.65, 1.39 0.780 0
Ileus 4 [6, 7, 13, 14] 28/306 (9.2 %) 47/936 (5.0 %) 1.33 0.81, 2.20 0.260 49.2
Wound infection 7 [6, 7, 11, 1316] 50/383 (13.1 %) 58/1265 (4.6 %) 2.22 1.47, 3.36 <0.001 0
Pulmonary events 5 [6, 7, 11, 14, 16] 23/297 (7.7 %) 28/765 (3.7 %) 2.10 1.18, 3.74 0.012 12.1
Deep venous thrombosis 2 [11, 14] 7/252 (2.8 %) 14/474 (3.0 %) 0.97 0.38, 2.43 0.941 0
Anastomotic leak 4 [7, 11, 14, 16] 20/250 (8.0 %) 12/539 (2.2 %) 3.94 1.88, 8.24 <0.001 0
Intraabdominal abscess 5 [7, 11, 13, 14, 16] 19/320 (5.9 %) 77/1022 (7.5 %) 1.10 0.65, 1.89 0.715 45.1
Intraabdominal haematoma 2 [11, 13] 5/142 (3.5 %) 18/603 (3.0 %) 0.65 0.24, 1.73 0.387 84
Fistula 3 [6, 11, 14] 5/276 (1.8 %) 27/660 (4.1 %) 1.15 0.40, 3.28 0.797 0
Reoperation 4 [6, 7, 11, 14] 14/283 (5.0 %) 46/679 (6.8 %) 0.79 0.43, 1.47 0.466 0
Cardiac complication 2 [11, 14] 19/252 (7.5 %) 29/474 (6.1 %) 1.17 0.63, 2.17 0.612 0
Renal failure 3 [7, 11, 14] 2/259 (0.8 %) 2/493 (0.4 %) 2.11 0.40, 11.03 0.378 0
Sexual dysfunction 2 [14, 16] 1/171 (0.6 %) 5/400 (1.3 %) 0.70 0.12, 4.25 0.699 0
Bladder dysfunction 2 [14, 16] 0/171 (0.0 %) 2/400 (0.5 %) 1.05 0.11, 10.27 0.965 0
Pathological results
Positive margin 5 [7, 11, 14, 17, 18] 19/472 (4.0 %) 61/1079 (5.7 %) 0.71 0.42, 1.20 0.197 0
Number of harvested nodes 5 [6, 11, 15, 17, 18]    0.07 −0.69, 0.83 0.852 0
  1. OR odds ratio, WMD weighted mean difference, CI confidence interval