From: Outcome of rectal cancer surgery in obese and nonobese patients: a meta-analysis
Outcome of interest | No. of studies | Events | OR/WMD | 95 % CI | P value | I 2 (%) | |
---|---|---|---|---|---|---|---|
Obese (%) | Nonobese (%) | ||||||
Operative outcomes | |||||||
Conversion rates | 26/92 (28.3 %) | 100/734 (13.6 %) | 2.78 | 1.67, 4.61 | <0.001 | 41.3 | |
Postoperative outcomes | |||||||
Overall morbidity | 1320/3259 (40.5 %) | 3264/9911 (32.9 %) | 1.36 | 1.25, 1.47 | <0.001 | 0 | |
Mortality | 34/3472 (1.0 %) | 109/10,329 (1.0 %) | 0.95 | 0.65, 1.39 | 0.780 | 0 | |
Ileus | 28/306 (9.2 %) | 47/936 (5.0 %) | 1.33 | 0.81, 2.20 | 0.260 | 49.2 | |
Wound infection | 50/383 (13.1 %) | 58/1265 (4.6 %) | 2.22 | 1.47, 3.36 | <0.001 | 0 | |
Pulmonary events | 23/297 (7.7 %) | 28/765 (3.7 %) | 2.10 | 1.18, 3.74 | 0.012 | 12.1 | |
Deep venous thrombosis | 7/252 (2.8 %) | 14/474 (3.0 %) | 0.97 | 0.38, 2.43 | 0.941 | 0 | |
Anastomotic leak | 20/250 (8.0 %) | 12/539 (2.2 %) | 3.94 | 1.88, 8.24 | <0.001 | 0 | |
Intraabdominal abscess | 19/320 (5.9 %) | 77/1022 (7.5 %) | 1.10 | 0.65, 1.89 | 0.715 | 45.1 | |
Intraabdominal haematoma | 5/142 (3.5 %) | 18/603 (3.0 %) | 0.65 | 0.24, 1.73 | 0.387 | 84 | |
Fistula | 5/276 (1.8 %) | 27/660 (4.1 %) | 1.15 | 0.40, 3.28 | 0.797 | 0 | |
Reoperation | 14/283 (5.0 %) | 46/679 (6.8 %) | 0.79 | 0.43, 1.47 | 0.466 | 0 | |
Cardiac complication | 19/252 (7.5 %) | 29/474 (6.1 %) | 1.17 | 0.63, 2.17 | 0.612 | 0 | |
Renal failure | 2/259 (0.8 %) | 2/493 (0.4 %) | 2.11 | 0.40, 11.03 | 0.378 | 0 | |
Sexual dysfunction | 1/171 (0.6 %) | 5/400 (1.3 %) | 0.70 | 0.12, 4.25 | 0.699 | 0 | |
Bladder dysfunction | 0/171 (0.0 %) | 2/400 (0.5 %) | 1.05 | 0.11, 10.27 | 0.965 | 0 | |
Pathological results | |||||||
Positive margin | 19/472 (4.0 %) | 61/1079 (5.7 %) | 0.71 | 0.42, 1.20 | 0.197 | 0 | |
Number of harvested nodes | 0.07 | −0.69, 0.83 | 0.852 | 0 |