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Table 3 Differential diagnosis

From: Clinicopathological characteristics of unicentric retroperitoneal Castleman’s disease: a study of 14 cases

 

Clinical manifestations

Pathological features

General features

Microscopic features

Castleman’s disease

Asymptomatic; may associated with autoimmune diseases; divided into unicentric type and multicentric type

Well-circumscribed, encapsulated mass, reddish-brown

Divided into hyaline-vascular type, plasma cell type and mixed type

Liposarcoma

Deep, painless, gradually grew tumor

Lobulated, multi-nodular, well defined

Divided into well-differentiated type, dedifferentiated type, myxoid type and pleomorphic type

Pheochromocytoma

High blood pressure, headaches, palpitations, high metabolic state, high blood sugar, sweating

Roundly, brown-yellow, internal hemorrhage, necrosis or cystic degeneration

Large irregular polygon cells, cells can be stained by chromium salts

Metastasis tumor

Different performances because of different primary tumors, lack of specificity

Various

Various