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Table 3 Differential diagnosis

From: Clinicopathological characteristics of unicentric retroperitoneal Castleman’s disease: a study of 14 cases

  Clinical manifestations Pathological features
General features Microscopic features
Castleman’s disease Asymptomatic; may associated with autoimmune diseases; divided into unicentric type and multicentric type Well-circumscribed, encapsulated mass, reddish-brown Divided into hyaline-vascular type, plasma cell type and mixed type
Liposarcoma Deep, painless, gradually grew tumor Lobulated, multi-nodular, well defined Divided into well-differentiated type, dedifferentiated type, myxoid type and pleomorphic type
Pheochromocytoma High blood pressure, headaches, palpitations, high metabolic state, high blood sugar, sweating Roundly, brown-yellow, internal hemorrhage, necrosis or cystic degeneration Large irregular polygon cells, cells can be stained by chromium salts
Metastasis tumor Different performances because of different primary tumors, lack of specificity Various Various