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Table 3 Treatment characteristics of 125I seed implantation and outcomes (n = 10)

From: Permanent interstitial 125I seed implantation as a salvage therapy for pediatric recurrent or metastatic soft tissue sarcoma after multidisciplinary treatment

No.

Metastasis

Size (cm)

Type of seeds implant

Seed activity (mCi)

No. of seeds/D90 (Gy)

Post-seed implant treatment

RR

LR (m)

Overall survival (m)

Causes of death

1

Yes

4.0 × 2.9 × 2.2

CDU

0.7

33/164.5

No

CR

107

Survival

1.3 × 1.5 × 1.0

CDU

0.7

6/148.1

No

CR

2

Yes

4.0 × 3.6 × 1.8

CDU

0.8

50/172.7

Seed implant after progress

PR

24

70

Survival

2.5 × 2.0 × 2.0

CDU

0.7

8/169.4

No

PR

1.8 × 1.2 × 1.0

CDU

0.65

9/171.6

No

PR

3

Yes

6.6 × 7.8 × 9.5

CT

0.72

158/187.0

No

PR

12

14

LR

4

No

3.2 × 3.3 × 1.5

CDU

0.7

30/176.0

No

CR

62

Survival

3.4 × 3.0 × 1.2

CDU

0.77

35/166.1

No

CR

5

No

3.2 × 2.9 × 2.0

CDU

0.8

54/174.9

No

PR

51

Survival

6

No

4.0 × 2.0 × 3.0

CDU

0.62

40/121.0

No

PR

41

Survival

7

Yes

3.8 × 3.5 × 3.0

CT

0.72

34/167.2

EBRT (50Gy)

SD

8

12

MM

8

Yes

3.5 × 4.9 × 12

CT

0.72

157/171.2

No

PR

3

6

MM

9

Yes

3.6 × 2.0 × 3.0

CT

0.66

27/132.0

No

PD

3

6

MM

10

No

5.8 × 2.8 × 5.0

CT

0.68

86/187.1

No

PR

7

Survival

  1. Abbreviations: CDU color Doppler ultrasound guided, CT computed tomography guided, EBRT, external beam radiotherapy, RR response rate, CR complete response, PR partial response, SD stable disease, PD progressive disease, m months, LR local recurrence, MM multiple metastasis