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Table 4 Clinical characteristics in n = 304 patients with no chemotherapy, perioperative and downsizing chemotherapy in conjunction with resection for colorectal liver metastases

From: Predictive factors for time to recurrence, treatment and post-recurrence survival in patients with initially resected colorectal liver metastases

Variable

No chemo (n = 199)

Perioperative (n = 59)

Downsizing (n = 46)

p

No. of mets (mean/median)

2.1/1

2.4/2

3.4/3

0.001a

Mets size (cm, median)

3.5/3

2.8/2.1

4.1/3.5

0.003a

Age (year, mean/median)

65.9/66.5

63.7/65.1

62.0/63.6

0.055b

R1 (n, %)

40 (20.2)

12 (20.7)

10 (21.7)

0.973c

N-pos primary (n, %)

68 (36.0)

19 (32.8)

21 (46.7)

0.311c

Clavien-Dindo (1–5)

61 (31.3)

24 (41.4)

16 (35.6)

0.350c

ASA (1/2/3)

20/136/43

5/50/4

2/34/10

0.069c

Synch. mets (n, %)

71 (35.7)

36 (61.0)

30 (65.2)

0.001c

Gender (M/F)

104/95

36/23

26/20

0.475c

Recurrence pattern (n, A/B)

53/82

15/18

20/15

0.256c

  1. Seven of 311 patients had progress on chemotherapy after stage III colon cancer, not included in the analysis
  2. A hepatic recurrence, B extrahepatic recurrence
  3. aKruskal-Wallis test
  4. bOne-way analysis of variance
  5. c χ 2 test