Overall recurrence (TTR) | |||||||
---|---|---|---|---|---|---|---|
Univariate | Multivariate | ||||||
Variable | n | HR | 95 % CI | p | HR | 95 % CI | p |
Age/10 years | 311 | 1.11 | (0.98, 1.26) | 0.113 | 1.08 | (0.94, 1.25) | 0.253 |
Synch. mets | |||||||
No | 154 | 1.00 | Reference | 0.002 | 1.00 | Reference | 0.010 |
Yes | 157 | 1.65 | (1.25, 2.17) | 1.50 | (1.10, 2.04) | ||
No. of mets | 311 | 1.21 | (1.14, 1.30) | <0.001 | 1.24 | (1.14, 1.34) | <0.001 |
Mets diam (cm) | 311 | 1.11 | (1.04, 1.18) | 0.002 | 1.08 | (1.01, 1.16) | 0.022 |
RM status | |||||||
R0 | 246 | 1.00 | Reference | 0.013 | 1.00 | Reference | 0.143 |
R1 | 63 | 1.53 | (1.11, 2.11) | 1.30 | (0.92, 1.84) | ||
ASA score (1–3) | 311 | 1.28 | (1.00, 1.65) | 0.054 | 1.40 | (1.05, 1.87) | 0.022 |
Clavien-Dindo | 311 | 1.12 | (1.01, 1.25) | 0.037 | 1.07 | (0.95, 1.20) | 0.267 |
N-posa | |||||||
No | 190 | 1.00 | Reference | 0.058 | 1.00 | Reference | 0.091 |
Yes | 109 | 1.32 | (0.99, 1.78) | 1.30 | (0.96, 1.77) | ||
Chemotherapy | |||||||
None | 199 | 1.00 | Reference | 0.010 | 1.00 | Reference | 0.014 |
Periop. | 59 | 0.71 | (0.49, 1.05) | 0.63 | (0.42, 0.95) | ||
Downsiz. | 46 | 1.31 | (0.90, 1.89) | 0.93 | (0.62, 1.39) | ||
Adj. colonb | 7 | 2.98 | (1.31, 6.79) | 2.80 | (1.21, 6.48) |