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Table 1 Clinical characteristics

From: Predictive factors for time to recurrence, treatment and post-recurrence survival in patients with initially resected colorectal liver metastases

Variable, statistics Estimate
Age in years, median (range) 66.1 (22.8, 91.3)
Gender males/females—ratio 169/142
Location primary tumour
 Colon, n (%) 205 (65.9)
 Rectum, n (%) 101 (32.5)
 Combined, n (%) 5 (1.6)
Synchronous metastasesa, n (%) 157 (50.5)
Disease-free intervalb in months, median (range) 4.2 (−11, 131)
Resections, n 311
 Hemihepatectomy/lobectomy, n (%) 137 (44.1)
 Wedge/segment resections, n (%) 174 (55.9)
 Simultaneous radio frequency ablation, n (%) 12 (3.9)
 Two-stage resections with PVL, n (%) 3 (1.0)
 Simultaneous colorectal cancer surgery, n (%) 18 (5.8)
R1 resections (<1 mm) 63 (20.3)
Extent of RM in millimeter, median (range) 4 (0–50)
Number of metastases, median (range) 2 (1, 12)
Metastases diameter in centimeter, median (range) 3.0 (0.2, 15.0)
Bilobar metastases, n (%) 108 (34.7)
Number of procedures/patient (1/2/3/4/5) 254/42/11/3/1
Morbidity (Clavien-Dindo score 1/2/3/4/5) 19/28/52/5/6
Outcome of chemotherapy (RECIST criteria)
 Partial response, n (%) 63 (56.2)
 Stable disease, n (%) 42 (37.5)
 Progression, n (%) 5 (4.4)
 Unknown, n (%) 2 (1.8)
  1. Unknown Clavien-Dindo score n = 1
  2. RM resection margin, RECIST Response Evaluation Criteria in Solid Tumour version 1.1
  3. aSynchronous metastases: detection of liver metastases within 3 months after primary colorectal resection
  4. bDisease-free interval: time between resection of the primary colorectal tumour and detection of CLM