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Table 1 Clinical characteristics

From: Predictive factors for time to recurrence, treatment and post-recurrence survival in patients with initially resected colorectal liver metastases

Variable, statistics

Estimate

Age in years, median (range)

66.1 (22.8, 91.3)

Gender males/females—ratio

169/142

Location primary tumour

 Colon, n (%)

205 (65.9)

 Rectum, n (%)

101 (32.5)

 Combined, n (%)

5 (1.6)

Synchronous metastasesa, n (%)

157 (50.5)

Disease-free intervalb in months, median (range)

4.2 (−11, 131)

Resections, n

311

 Hemihepatectomy/lobectomy, n (%)

137 (44.1)

 Wedge/segment resections, n (%)

174 (55.9)

 Simultaneous radio frequency ablation, n (%)

12 (3.9)

 Two-stage resections with PVL, n (%)

3 (1.0)

 Simultaneous colorectal cancer surgery, n (%)

18 (5.8)

R1 resections (<1 mm)

63 (20.3)

Extent of RM in millimeter, median (range)

4 (0–50)

Number of metastases, median (range)

2 (1, 12)

Metastases diameter in centimeter, median (range)

3.0 (0.2, 15.0)

Bilobar metastases, n (%)

108 (34.7)

Number of procedures/patient (1/2/3/4/5)

254/42/11/3/1

Morbidity (Clavien-Dindo score 1/2/3/4/5)

19/28/52/5/6

Outcome of chemotherapy (RECIST criteria)

 Partial response, n (%)

63 (56.2)

 Stable disease, n (%)

42 (37.5)

 Progression, n (%)

5 (4.4)

 Unknown, n (%)

2 (1.8)

  1. Unknown Clavien-Dindo score n = 1
  2. RM resection margin, RECIST Response Evaluation Criteria in Solid Tumour version 1.1
  3. aSynchronous metastases: detection of liver metastases within 3 months after primary colorectal resection
  4. bDisease-free interval: time between resection of the primary colorectal tumour and detection of CLM