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Table 4 Multivariate analyses of progression-free survival (PFS) and overall survival (OS) in patients with breast carcinoma

From: Overexpression of G6PD is associated with high risks of recurrent metastasis and poor progression-free survival in primary breast carcinoma

Variables PFS OS
P value Hazard ratio (HR) 95 % CI P value HR 95 % CI
G6PD (negative vs. positive expression) 0.021 13.488 1.472–123.554 0.398 2.695 0.271–26.815
PKM2 (negative vs. positive expression) 0.835 1.304 0.107–15.868 0.674 1.916 0.093–39.686
Tumor staging       
 I 0.095    0.977   
 II 0.241 0.262 0.028–2.461 0.963
 III 0.375 2.691 0.303–23.938 0.964
Tumor size (≤2 cm vs. >2 cm) 0.946 0.000 0.900
  1. Cox regression analysis (Enter method) was used to assess prognostic factors associated with PFS and OS. A hazard ratio >1 with P < 0.05 indicates a greater likelihood of development of breast carcinoma, while a hazard ratio <1 with P < 0.05 indicates a lesser likelihood of development of breast carcinoma. A hazard ratio = 1 with P < 0.05 indicates that the given factor could not affect the development of breast carcinoma, but was significant in multivariate logistic regression model