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Table 3 Correlation between clinicopathological features and the protein expression of G6PD and PKM2 in patients with breast carcinoma

From: Overexpression of G6PD is associated with high risks of recurrent metastasis and poor progression-free survival in primary breast carcinoma

Indicators G6PD P value PKM2 P value
Negative Positive Negative Positive
Mean age (n)    0.111    0.891
 ≤0 years 10 4   2 12  
 >60 years 2 4   1 5  
Lymph node metastasis (n)    0.763    0.001
 0 2 2   3 1  
 ≤3 4 3   0 9  
 >3 6 3   0 7  
Molecular subtypes (n)    0.444    0.948
 Luminal A 5 2   1 6  
 Luminal B 7 6   2 11  
Tumor staging (n)    0.058    0.277
 I 0 3   1 2  
 II 7 2   2 7  
 III 5 3   0 8  
Tumor size (n)    0.070    0.306
 ≤2 cm 5 7   1 11  
 >2 cm 7 1   2 6  
Pathological classification (n)    0.224    0.531
 IDC stage I 2 0   0 2  
 IDC stage II 10 8   3 15  
  1. Stage I, T1N0M0; stage II, T0-1N1M0, T2N0-1M0, and T3N0M0; stage III, T0-2N2M0, T3N1-2M0, T4N0-3M0, and T0-4N3M0; IDC, infiltrating duct carcinoma. P < 0.5 was considered statistically significant