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Table 3 Correlation between clinicopathological features and the protein expression of G6PD and PKM2 in patients with breast carcinoma

From: Overexpression of G6PD is associated with high risks of recurrent metastasis and poor progression-free survival in primary breast carcinoma

Indicators

G6PD

P value

PKM2

P value

Negative

Positive

Negative

Positive

Mean age (n)

  

0.111

  

0.891

 ≤0 years

10

4

 

2

12

 

 >60 years

2

4

 

1

5

 

Lymph node metastasis (n)

  

0.763

  

0.001

 0

2

2

 

3

1

 

 ≤3

4

3

 

0

9

 

 >3

6

3

 

0

7

 

Molecular subtypes (n)

  

0.444

  

0.948

 Luminal A

5

2

 

1

6

 

 Luminal B

7

6

 

2

11

 

Tumor staging (n)

  

0.058

  

0.277

 I

0

3

 

1

2

 

 II

7

2

 

2

7

 

 III

5

3

 

0

8

 

Tumor size (n)

  

0.070

  

0.306

 ≤2 cm

5

7

 

1

11

 

 >2 cm

7

1

 

2

6

 

Pathological classification (n)

  

0.224

  

0.531

 IDC stage I

2

0

 

0

2

 

 IDC stage II

10

8

 

3

15

 
  1. Stage I, T1N0M0; stage II, T0-1N1M0, T2N0-1M0, and T3N0M0; stage III, T0-2N2M0, T3N1-2M0, T4N0-3M0, and T0-4N3M0; IDC, infiltrating duct carcinoma. P < 0.5 was considered statistically significant