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Table 2 The expressions of CYP27A1, CYP7B1, IGF-1, G6PD, GFPT1, and PKM2 in tumor specimens of patients with breast carcinoma

From: Overexpression of G6PD is associated with high risks of recurrent metastasis and poor progression-free survival in primary breast carcinoma

  Group A (n = 10) Group AM (n = 10) Group B (n = 10) P value
CYP27A1 (n)     0.240
 Negative 5 8 8  
 Positive 5 2 2  
CYP7B1 (n)     0.585
 Negative 0 1 1  
 Positive 10 9 9  
IGF-1 (n)     0.315
 Negative 8 8 10  
 Positive 2 2 0  
G6PD (n)     0.010
 Negative 3 8 9  
 Positive 7 2 1  
GFPT1 (n)     0.082
 Negative 8 10 6  
 Positive 2 0 4  
PKM2 (n)     0.036
 Negative 1 6 2  
 Positive 9 4 8  
  1. Group A, primary breast carcinoma with recurrent metastasis during the follow-up; Group AM, corresponding recurrent metastases; Group B, primary breast carcinoma with no pathological evidence of recurrence or metastasis. P < 0.5 was considered statistically significant