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Table 2 Raw data and methodological quality of included trials

From: Thoracic perfusion of matrine as an adjuvant treatment improves the control of the malignant pleural effusions

Studies

Region

Sequence generation

Allocation concealment

Blind

Outcome data

Selective outcome reporting

Other sources of bias

ITT

Risk of bias

Yunfang et al. [15]

Single center

Random number table (SAS)

Insufficient

Clear

No

No

Unclear

Yes

Low risk of bias

Sijie et al. [13]

Single center

Random number table (SPSS)

Unclear

Unclear

Yes

No

Clear

No

Unclear risk of bias

Zenmin et al. [9]

Single center

Random number table (SPSS)

Insufficient

Unclear

Yes

No

Unclear

No

Low risk of bias

Daiju and Xiaodong [19]

Single center

unclear

Unclear

Clear

Yes

No

Unclear

No

Unclear risk of bias

Zhiwen et al. [12]

Single center

Random number table (SPSS)

Unclear

Unclear

Yes

No

Clear

No

Unclear risk of bias

Liangfa et al. [11]

Single center

Random number table (SPSS)

Clear

Clear

Yes

No

Clear

No

Unclear risk of bias

Xiaowei et al. [10]

Single center

Random number table (SPSS)

Insufficient

Unclear

Yes

No

Clear

No

Unclear risk of bias

Guoan [18]

Single center

Random number table (SPSS)

Clear

Unclear

Yes

Yes

Clear

No

Unclear risk of bias

Li [8]

Single center

Random number table (SAS)

Insufficient

Unclear

Yes

No

Clear

No

Unclear risk of bias

Ziqiang [14]

Single center

Random number table (SPSS)

Unclear

Unclear

Yes

No

Unclear

No

Unclear risk of bias

Yushun and Jie [16]

Single center

Random number table (SPSS)

Insufficient

Clear

Yes

No

Unclear

No

Low risk of bias

Zhenfeng et al. [17]

Single center

Random number table (SPSS)

Clear

Clear

Yes

No

Clear

No

Unclear risk of bias

  1. SAS SAS software, SPSS SPSS software, ITT intention-to-treat