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Table 2 Raw data and methodological quality of included trials

From: Thoracic perfusion of matrine as an adjuvant treatment improves the control of the malignant pleural effusions

Studies Region Sequence generation Allocation concealment Blind Outcome data Selective outcome reporting Other sources of bias ITT Risk of bias
Yunfang et al. [15] Single center Random number table (SAS) Insufficient Clear No No Unclear Yes Low risk of bias
Sijie et al. [13] Single center Random number table (SPSS) Unclear Unclear Yes No Clear No Unclear risk of bias
Zenmin et al. [9] Single center Random number table (SPSS) Insufficient Unclear Yes No Unclear No Low risk of bias
Daiju and Xiaodong [19] Single center unclear Unclear Clear Yes No Unclear No Unclear risk of bias
Zhiwen et al. [12] Single center Random number table (SPSS) Unclear Unclear Yes No Clear No Unclear risk of bias
Liangfa et al. [11] Single center Random number table (SPSS) Clear Clear Yes No Clear No Unclear risk of bias
Xiaowei et al. [10] Single center Random number table (SPSS) Insufficient Unclear Yes No Clear No Unclear risk of bias
Guoan [18] Single center Random number table (SPSS) Clear Unclear Yes Yes Clear No Unclear risk of bias
Li [8] Single center Random number table (SAS) Insufficient Unclear Yes No Clear No Unclear risk of bias
Ziqiang [14] Single center Random number table (SPSS) Unclear Unclear Yes No Unclear No Unclear risk of bias
Yushun and Jie [16] Single center Random number table (SPSS) Insufficient Clear Yes No Unclear No Low risk of bias
Zhenfeng et al. [17] Single center Random number table (SPSS) Clear Clear Yes No Clear No Unclear risk of bias
  1. SAS SAS software, SPSS SPSS software, ITT intention-to-treat