Table 3 Univariate and multivariate Cox proportional hazards analyses for biochemical recurrence-free survival
Variables | HR (95 % CI) | P value |
|---|---|---|
Univariate | ||
Age | 0.976(0.935–1.019) | 0.269 |
BMI (continuous) | 1.107(0.999–1.227) | 0.053 |
BMI (categorical, kg/m2) | ||
<23 | Reference | – |
23–24.9 | 1.237(0.588–2.603) | 0.575 |
≥25 | 2.087(1.033–4.215) | 0.040 |
Preoperative PSAa | 1.509(1.040–2.190) | 0.030 |
PVa | 1.421(0.697–2.894) | 0.333 |
DRE | 1.518(0.860–2.679) | 0.15 |
TRUS | 0.946(0.505–0.1.770) | 0.862 |
Clinical stage | 1.308(0.653–2.619) | 0.448 |
Pathological GS (≥7) | 1.133(0.597–2.152) | 0.702 |
Positive surgical margin | 0.810(0.290–2.263) | 0.688 |
Extra capsular invasion | 1.067(0.453–2.514) | 0.883 |
Seminal vesicle invasion | 1.994(0.779–5.105) | 0.150 |
Lymph node invasion | 2.835(0.872–9.218) | 0.083 |
Multivariate model I | ||
BMI (continuous) | 1.145(1.029–1.273) | 0.013 |
Age | 0.972(0.929–1.017) | 0.225 |
PSAa | 1.659(1.102–2.497) | 0.015 |
Pathological GS (≥7) | 0.991(0.512–1.917) | 0.978 |
Positive surgical margin | 0.442(0.148–1.316) | 0.142 |
Multivariate model II | ||
BMI (categorical, kg/m2) | ||
<23 | Reference | – |
23–24.9 | 1.583(0.720–3.482) | 0.253 |
≥25 | 2.937(1.383–6.237) | 0.005 |
Age | 0.971(0.926–1.018) | 0.217 |
PSAa | 1.725(1.132–2.628) | 0.011 |
Pathological GS (≥7) | 1.009(0.525–1.938) | 0.979 |
Positive surgical margin | 0.428(0.144–1.270) | 0.126 |