Endoscopic submucosal dissection for early gastric cancer in elderly patients: a meta-analysis

Table 1 Characteristics of included studies

Study	Period	Country	Study design	Group	Sample size	Mean age	Gender (M/F)	Comorbidity (%)	Ulcer findings	Location (U/M/L)	Invasion depth (S/SM)	Tumor size (mm)	Comparability of baseline characteristics	Study quality score
Hirasaki [13]	2000–2004	Japan	R	E	53	78.2	34/19	57	NR	NR	47/6	12.2	abf	6
				NE	91	64.7	74/17	33	NR	NR	83/8	13	abf	6
Shimura [14]	2002–2006	Japan	R	E	45	NR	33/8	65.9	NR	6/25/14	NR	16	abc	7
				NE	80	NR	57/18	31.3	NR	11/36/33	NR	NR	abc	7
Kakushima [15]	2000–2004	Japan	R	E	49	NR	NR	NR	NR	NR	NR	NR	NR	6
				NE	135	NR	NR	NR	NR	NR	NR	NR	NR	6
Onozato [16]	2002–2006	Japan	R	E	110	79.8	50/43	NR	14/96	18/45/47	102/8	22.8	bcef	6
				NE	141	66	106/27	NR	24/117	25/35/81	114/27	21.8	bcef	6
Isomoto [17]	2001–2007	Japan	R	E	279	NR	173/106	NR	3.7	44/129/105	222/57	20	bcf	6
				NE	434	NR	343/91	NR	13.3	73/209/149	369/65	19	bcf	6
Toyokawa [18]	2003–2009	Japan	R	E	229	80	128/72	153	11.8	54/76/98	158/28	19	bcdef	8
				NE	357	66	237/77	93.66	10.1	93/141/122	245/41	18	bcdef	8
Tokioka [19]	2002–2010	Japan	R	E	372	73.9	260/112	115.3	NR	25/109/229	367/5	15.1	abcdf	7
				NE	143	57.7	118/25	58.8	NR	23/45/74	138/5	14.5	abcdf	7
Murata [20]	2009–2010	Japan	R	E	5525	NR	3619/1906	61.7	NR	569/2801/2155	NR	NR	NR	6
				NE	21,860	NR	16,657/5203	44.4	NR	1880/12,001/7979	NR	NR	NR	6
Zhang [21]	2010–2013	China	R	E	51	79	33/13	76.1	11/51	9/17/24	40/11	19	abcde	8
				NE	136	59.4	79/46	37.6	21/136	9/44/83	129/7	20	abcde	8

M male, F female, L lower third of stomach, M middle third of stomach, U upper third of stomach, E elderly group, NE non-elderly group, R retrospective, NR not report, a gender, b tumor size, c tumor location, d macroscopic types, e ulcer findings, f invasion depth

ISSN: 1477-7819