Table 2 Relationship of Hoxd10 expression with pathological parameters of tumor

Age (years)

59.77 ± 12.44

58.48 ± 11.85

1.107

0.269

Gender

0.519

0.4771

 Male

135 (43.4 %)

176 (56.6 %)

 Female

59 (47.2 %)

66 (52.8 %)

Location

4.379

0.112

 Proximal

31 (56.4 %)

24 (43.6 %)

 Middle

74 (45.4 %)

89 (54.6 %)

 Distal

89 (40.8 %)

129 (59.2 %)

Size

25.716

0.0001

 <5 cm

88 (34.4 %)

168 (65.6 %)

 ≥5 cm

106 (58.9 %)

74 (41.1 %)

Lauren classification

63.165

0.0001

 Intestinal

58 (26.0 %)

165 (74.0 %)

 Diffuse

136 (63.8 %)

77 (36.2 %)

Histology classification

7.343

0.062

 Papillary adenocarcinoma

3 (18.8 %)

13 (81.2 %)

 Tubular adenocarcinoma

142 (43.6 %)

184 (56.4 %)

 Mucinous adenocarcinoma

17 (58.6 %)

12 (41.4 %)

 Signet-ring cell carcinoma

32 (49.2 %)

33 (50.8 %)

Histologic differentiation

5.25

0.154

 Well

3 (23.1 %)

10 (76.9 %)

 Moderately

50 (39.1 %)

78 (60.9 %)

 Poorly

140 (47.8 %)

153 (52.2 %)

 Others

1 (50.0 %)

1 (50.0 %)

Invasion depth

33.892

0.0001

 T1

9 (15.8 %)

48 (84.2 %)

 T2

39 (35.8 %)

70 (64.2 %)

 T3

129 (52.9 %)

115 (47.1 %)

 T4

17 (65.4 %)

9 (34.6 %)

TNM stages

60.859

0.0001

 I

17 (18.9 %)

73 (81.1 %)

 II

30 (28.8 %)

74 (71.2 %)

 III

102 (59.0 %)

71 (41.0 %)

 IV

45 (65.2 %)

24 (34.8 %)

Lymphatic metastasis

45.165

0.0001

 No

40 (24.1 %)

126 (75.9 %)

 Yes

154 (57.0 %)

116 (43.0 %)

Regional lymph nodes

51.95

0.0001

 PN0

40 (24.1 %)

126 (75.9 %)

 PN1

67 (49.3 %)

69 (50.7 %)

 PN2

65 (65.7 %)

34 (34.3 %)

 PN3

22 (62.9 %)

13 (37.1 %)

Distant metastasis

14.821

0.0001

 No

153 (40.8 %)

222 (59.2 %)

 Yes

41 (67.2 %)

20 (32.8 %)