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Table 2 Prediction of survival and recurrence of patients with a single nodule of SHCC following curative resection

From: Preoperative neutrophil-to-lymphocyte ratio predicts recurrence of patients with single-nodule small hepatocellular carcinoma following curative resection: a retrospective report

Factors OS TTR
Univariate multivariate Univariate multivariate
P HR (95 % CI) P P HR (95 % CI) P
Age (≤53 vs >53) NS   NA 0.004   NS
AFP(≤20 vs >20) NS   NA 0.043   NS
INR (≤1.0 vs >1.0) 0.010   NS NS   NA
PLT counts (≤127 vs >127) 0.046   NS NS   NA
Neutrophil counts 0.040 0.329 (0.174–0.623) 0.001 NS   NA
Vascular invasion (yes vs no) NS   NA 0.001 1.757 (1.110–2.781) 0.016
Tumor size (≤3.0 vs >3.0) 0.040   NS <0.001   NS
Postoperative TACE (yes vs no) 0.001 2.566 (1.488–4.424) 0.001 <0.001 2.175 (1.408–3.359) <0.001
Re-operation (yes vs no) NS   NA <0.001 9.037 (4.970–16.432) <0.001
NLR (>2.1 vs ≤2.1) 0.014 3.013 (1.633–5.561) <0.001 0.002 1.619 (1.057–2.478) 0.027
  1. Univariate analysis Kaplan-Meier method, Multivariate analysis Cox proportional hazards regression model, SHCC small hepatocellular carcinoma, AFP alpha-fetoprotein, INR international normal ratio, PLT platelet, TACE transarterial chemoembolization, NLR neutrophil-to-lymphocyte ratio, OS overall survival, TTR time to recurrence, HR hazard ratio, NS not significant, NA not adopted