Clinicopathological significance of KAI1 expression and epithelial-mesenchymal transition in non-small cell lung cancer

Table 2 KAI1 and EMT and vascular endothelial and lymphatic endothelial marker as predictors for lymph node metastasis in 312 NSCLC patients (X ²)

Marker expression	Patients (n)	N0 (n)	N1 (n)	N2 (n)	P(X ²)N0 Verse N1 Verse N2	P(X ²)N0 Verse N+	P(X ²) N0 + N1 Verse N2
KAI1					<0.001	<0.001	<0.001
Negative	206	84	80	42
Positive	106	69	34	3
Co-expression					<0.001	<0.001	<0.001
Low V/high E	114	75	36	3
Low V/low E	66	29	33	4
High V/high E	10	5	2	3
High V/low E	122	44	43	35
MVD score					<0.001	<0.001	<0.001
Mean	21.6 ± 12.0	18.0 ± 11.5	23.4 ± 11.0	29.2 ± 11.2
LVD score					<0.001	0.005	<0.001
Mean	4.8 ± 2.8	4.4 ± 2.7	4.9 ± 2.7	6.2 ± 2.5

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