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Table 2 The roles of node-associated factors in predicting overall survival outcome for patients with ampullary carcinoma undergoing curative pancreaticoduodenectomy

From: The role of lymph nodes in predicting the prognosis of ampullary carcinoma after curative resection

Variables No. of patients n (%) Survival Univariate analysis Multivariate analysis
5-year (%) Median (months) Mean ± SD (months) P value Hazard ratio 95 % CI P value
Nodal status      <0.001    0.036
 Negative 122 (62.9) 53.9 79.5 98.5 ± 7.9   (Ref.)  
 Positive 72 (37.1) 20.3 28.5 53.4 ± 8.6   2.12 1.05–4.26
THLN number      0.037    0.028
 <14 148 (76.3) 38.9 41.8 73.9 ± 6.9   (Ref.)  
 ≥14 46 (23.7) 56.9 109.9 ± 13.5   0.49 0.26–0.93
Positive LN number      0.004    0.938
 <2 150 (77.3) 47.2 54.4 90.3 ± 7.2   (Ref.)  
 ≥2 44 (22.7) 25.4 25.7 58.3 ± 11.5   1.03 0.50–2.14
LNR      <0.001    0.665
 <0.15 147 (75.8) 50.3 71.8 94.6 ± 7.3   (Ref.)  
 ≥0.15 47 (24.2) 18.0 26.2 46.4 ± 8.6   1.20 0.53–2.75
  1. THLN total harvested lymph node, LN lymph node, LNR lymph node ratio, SD standard deviation, CI confidence interval