Skip to main content

Table 3 Baseline characteristics of 1095 colorectal cancer patients stratified by stage and tumor location

From: Different clinicopathologic features and favorable outcomes of patients with stage III left-sided colon cancer

Characteristic Stage I Stage II Stage III Stage IV
  Right-sided colon (%) Left-sided colon (%) P value Right-sided colon (%) Left-sided colon (%) P value Right-sided colon (%) Left-sided colon (%) P value Right-sided colon (%) Left-sided colon (%) P value
N = 28 (14.6 %) N = 164 (85.3 %) N = 101 (26.1 %) N = 286 (73.9 %) N = 80 (24.2 %) N = 251 (75.8 %) N = 40 (21.4 %) N = 145 (78.4 %)
Age (years, mean ± SD) 67.36 ± 10.05 65.04 ± 13.20 0.289 65.90 ± 13.67 65.30 ± 12.15 0.678 61.99 ± 14.86 61.90 ± 13.21 0.959 66.70 ± 11.57 62.85 ± 12.77 0.087
Gender    0.603    0.244    0.751    0.011*
 Female 12 (42.9) 79 (48.2) 52 (47.3) 128 (40.9) 37 (46.3) 111 (44.2) 23 (57.5) 51 (35.2)
 Male 16 (57.1) 85 (51.8) 58 (52.7) 185 (59.1) 43 (53.8) 140 (55.8) 17 (42.5) 94 (64.8)
Tumor size    1.000    0.060    0.070    0.921
  < 5 cm 24 (85.7) 139 (85.8) 42 (41.6) 150 (52.4) 37 (46.3) 144 (57.8) 18 (46.2) 62 (45.3)
  ≥ 5 cm 4 (14.3) 23 (14.2) 59 (58.4) 136 (47.6) 43 (53.8) 105 (42.2) 21 (53.8) 75 (54.7)
Histology    0.195    0.002*    0.036*    0.517
 Well 10 (35.7) 32 (20.3) 6 (6.1) 11 (3.9) 3 (3.9) 5 (2.0) 1 (2.6) 3 (2.2)
 Moderately 17 (60.7) 120 (75.9) 76 (76.8) 255 (90.1) 57 (74.0) 212 (86.5) 31 (79.5) 117 (86.7)
 Poorly 1 (3.6) 6 (3.8) 17 (17.2) 17 (6.0) 17 (22.1) 28 (11.4) 7 (17.9) 15 (11.1)
Tumor depth    0.872    0.197    0.457    0.858
 T1 10 (35.7) 56 (34.1) 0 (0.0) 0 (0.0) 2 (2.5) 2 (0.8) 0 (0.0) 1 (0.7)
 T2 18 (64.3) 108 (65.9) 0 (0.0) 0 (0.0) 5 (6.3) 25 (10.0) 1 (2.6) 6 (4.3)
 T3 0 (0.0) 0 (0.0) 101 (100.0) 279 (97.6) 67 (83.8) 209 (83.3) 31 (79.5) 103 (74.1)
 T4 0 (0.0) 0 (0.0) 0 (0.0) 7 (2.4) 6 (7.5) 15 (6.0) 7 (17.9) 29 (20.9)
Lymph Node metastasis       0.158   0.813
 N0 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0) 13 (33.3) 41 (30.1)
 N1 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0) 49 (61.3) 175 (69.7) 13 (33.3) 42 (30.9)
 N2 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0) 31 (38.8) 76 (30.3) 13 (33.3) 53 (39.0)
Vascular invasion    0.695    0.133    0.110    0.510
 No 27 (96.4) 146 (92.4) 83 (82.2) 211 (74.8) 39 (48.8) 145 (58.9) 14 (38.9) 59 (45.0)
 Yes 1 (3.6) 12 (7.6) 18 (17.8) 71 (25.2) 41 (51.2) 101 (41.1) 22 (61.1) 72 (55.0)
Perineural invasion    0.473    0.861    0.512    0.790
 No 27 (96.4) 143 (90.5) 67 (66.3) 185 (65.4) 47 (59.5) 136 (55.3) 16 (42.1) 52 (39.7)
 Yes 1 (3.6) 15 (9.5) 34 (33.7) 98 (34.6) 32 (40.5) 110 (44.7) 22 (57.9) 79 (60.3)
Pre-op serum CEAa level    0.560    0.237    0.043*    0.410
  < 5 ng/ml 22 (81.5) 127 (85.8) 62 (62.6) 150 (55.8) 28 (38.4) 122 (51.9) 9 (25.0) 25 (18.8)
  ≥ 5 ng/ml 5 (18.5) 21 (14.2) 37 (37.4) 119 (44.2) 45 (61.6) 113 (48.1) 27 (75.0) 108 (81.2)  
Post-op serum CEAa level    0.697    0.158    0.025*    0.764
  < 5 ng/ml 24 (96.0) 140 (92.1) 75 (79.8) 232 (85.9) 49 (64.5) 185 (77.4) 10 (27.0) 37 (29.6)
  ≥ 5 ng/ml 1 (4.0) 12 (7.9) 19 (20.2) 38 (14.1) 27 (35.5) 54 (22.6) 27 (73.0) 88 (70.4)
Pre-op serum Albumin level (g/dl) 3.72 ± 0.37 3.76 ± 0.39 0.664 3.46 ± 0.47 3.58 ± 0.46 0.030 3.68 ± 0.37 3.69 ± 0.40 0.887 3.48 ± 0.45 3.46 ± 0.50 0.885
Diabetes mellitus    0.307   0.841   0.920   0.844
 Yes 9 (32.1) 38 (23.2) 24 (23.8) 69 (24.1) 19 (23.8) 61 (24.3) 8 (20.0) 27 (18.6)
 No 19 (67.9) 126 (76.8) 77 (76.2) 217 (75.9) 62 (76.2) 190 (75.7) 32 (80.0) 118 (81.4)
Chemotherapy       0.030*    0.852    0.817
 Yes 53 (52.5) 185 (64.7) 72 (91.1) 227 (90.4) 33(82.6) 121 (84.0)
 No 48 (47.5) 101 (35.3) 7 (8.9) 24 (9.6) 7 (17.5) 23 (16.0)
Cardiac disease    0.257    0.365    0.772    0.976
 Yes 15 (53.6) 69 (42.1) 41 (40.6) 131 (45.8) 32 (40.0) 105 (41.8) 15 (37.5) 54 (37.2)
 No 13 (46.4) 95 (57.9) 60 (59.4) 156 (54.2) 48 (60.0) 146 (58.2) 25 (62.5) 91 (62.8)
Renal disease    0.127*    0.693    0.450    1.000
 Yes 3 (10.7) 6 (3.7) 6 (5.9) 14 (4.9) 2 (2.5) 11 (4.4) 2 (5.0) 8 (5.5)
 No 25 (89.3) 158 (96.3) 95 (94.1) 272 (95.1) 78 (97.5) 240 (95.6) 38 (95.0) 137 (94.5)
BMIb 23.94 ± 3.88 23.70 ± 3.73 0.748 23.80 ± 4.39 23.73 ± 3.73 0.092 23.71 ± 4.13 23.95 ± 3.44 0.616 22.23 ± 4.31 22.77 ± 3.50 0.418
  1. aCEA Carcinoembryonic antigen, bBMI Body mass index, *Indicated P < 0.05