Characteristic | Univariate | Multivariate | ||
---|---|---|---|---|
HR (95Â % CI) | p value | HR (95Â % CI) | p value | |
Sex | 1.046 (0.688–1.589) | 0.835 |  |  |
Age | 1.011 (0.988–1.034) | 0.360 |  |  |
PT–INR | 7.894 (1.041–59.841) | 0.046 |  |  |
Type of resection | Â | 0.483 | Â | Â |
 Wedge resection | 0.917 (0.223–9.767) | 0.904 |  |  |
 Segmentectomy | 1.264 (0.601–2.661) | 0.537 |  |  |
 Multiple segmentectomy | 0.729 (0.399–1.335) | 0.306 |  |  |
 Hemihepatectomy | 1 |  |  |  |
 Extended hemihepatectomy | 1.419 (0.799–2.518) | 0.232 |  |  |
Tumor subtype | 0.386 (0.221–0.676) | 0.001 |  |  |
Histology | 0.394 (0.144–1.075) | 0.069 |  |  |
Tumor size ≥4.0 cm | 2.932 (1.830–4.696) | <0.001 | 2.522 (1.556–4.088) | <0.001 |
Multiple tumors | 2.020 (1.279–3.191) | 0.003 | 1.815 (1.125–2.927) | 0.015 |
LVI | 1.866 (1.232–2.826) | 0.003 |  |  |
PNI | 1.825 (1.156–2.880) | 0.010 |  |  |
LN metastasis | 2.277 (1.424–3.642) | 0.001 | 2.004 (1.221–3.289) | 0.006 |
Resection margin | 0.988 (0.972–1.044) | 0.144 |  |  |
HBV | 1.135 (0.685–1.881) | 0.623 |  |  |
HCV | 1.550 (0.624–3.849) | 0.345 |  |  |