Comparison of the 6th and 7th editions of the AJCC/UICC TNM staging system for gastric cancer focusing on the “N” parameter-related survival: the monoinstitutional NodUs Italian study

Table 2 Two multivariate analysis models of overall survival in gastric cancer patients

Variables	Hazard ratio	95 % CI	P value
(a) 6th AJCC N staging system (−2 log likelihood: 1548.021; linear trend χ ²: 1501.231; AIC value: 2591.3)
Age at surgery	1.025	0.748–1.598	0.652
Tumor location	0.984	0.548–1.746	0.985
Histological grade	0.745	0.624–1.348	0.015
Lauren’s classification	0.864	0.521–1.681	0.312
The 6th N stage (AJCC)	1.256	0.894–1.612	0.007
(b) 7th AJCC N staging system (−2 log likelihood: 1541.013; linear trend χ ²: 1498.564; AIC value: 2601.4)
Age at surgery	1.101	0.809–1.494	0.884
Tumor location	1.003	0.756–1.319	0.731
Histological grade	0.639	0.517–1.214	0.021
Lauren’s classification	0.931	0.611–1.306	0.424
The 7th N stage (AJCC)	1.481	1.112–2.031	0.011

95 % CI 95 % confidence interval, AJCC American Joint Committee on Cancer, AIC Akaike information criterion, N node

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