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Table 1 Univariate survival analysis of clinicopathological variables in 274 gastric cancer patients

From: Comparison of the 6th and 7th editions of the AJCC/UICC TNM staging system for gastric cancer focusing on the “N” parameter-related survival: the monoinstitutional NodUs Italian study

  N (%) 5-year survival rate (%) Log-rank χ 2 value P value
Gender    1.987 0.159
 Female 95 (34.7) 50.6   
 Male 179 (65.3) 42.7   
Age at surgery (years)    3.247 0.047
 ≤40 14 (5.1) 80.0   
 41–60 90 (32.8) 41.9   
 >61 170 (62.1) 44.5   
Tumor location    4.786 0.025
 Upper 77 (28.1) 43.1   
 Upper-middle 34 (12.4) 38.7   
 Middle 72 (26.3) 42.9   
 Middle-lower 29 (10.6) 41.7   
 Lower 62 (22.6) 56.4   
Histological grade    6.788 0.009
 Well + moderately differentiated 129 (47.1) 51.7   
 Poorly differentiated + signet ring cell 145 (52.9) 38.7   
Lauren’s classification    9.772 0.002
 Intestinal type 104 (38.0) 54.7   
 Diffuse type 170 (62.0) 39.7   
Type of gastrectomy    0.656 0.199
 Subtotal 40 (14.6) 47.1   
 Total 234 (85.4) 45.2   
The 6th N stage (AJCC)    17.013 0.002
 N0 66 (23.9) 66.0   
 N1 103 (37.6) 52.1   
 N2 61 (22.2) 50.0   
 N3 44 (16.2) 31.0   
The 7th N stage (AJCC)    29.483 0.0003
 N0 66 (23.9) 66.0   
 N1 44 (16.2) 66.7   
 N2 71 (26.1) 48.1   
 N3a 60 (21.8) 51.2   
 N3b 33 (12.0) 20.8   
  1. AJCC American Joint Committee on Cancer, N node