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Table 1 Univariate survival analysis of clinicopathological variables in 274 gastric cancer patients

From: Comparison of the 6th and 7th editions of the AJCC/UICC TNM staging system for gastric cancer focusing on the “N” parameter-related survival: the monoinstitutional NodUs Italian study

 

N (%)

5-year survival rate (%)

Log-rank χ 2 value

P value

Gender

  

1.987

0.159

 Female

95 (34.7)

50.6

  

 Male

179 (65.3)

42.7

  

Age at surgery (years)

  

3.247

0.047

 ≤40

14 (5.1)

80.0

  

 41–60

90 (32.8)

41.9

  

 >61

170 (62.1)

44.5

  

Tumor location

  

4.786

0.025

 Upper

77 (28.1)

43.1

  

 Upper-middle

34 (12.4)

38.7

  

 Middle

72 (26.3)

42.9

  

 Middle-lower

29 (10.6)

41.7

  

 Lower

62 (22.6)

56.4

  

Histological grade

  

6.788

0.009

 Well + moderately differentiated

129 (47.1)

51.7

  

 Poorly differentiated + signet ring cell

145 (52.9)

38.7

  

Lauren’s classification

  

9.772

0.002

 Intestinal type

104 (38.0)

54.7

  

 Diffuse type

170 (62.0)

39.7

  

Type of gastrectomy

  

0.656

0.199

 Subtotal

40 (14.6)

47.1

  

 Total

234 (85.4)

45.2

  

The 6th N stage (AJCC)

  

17.013

0.002

 N0

66 (23.9)

66.0

  

 N1

103 (37.6)

52.1

  

 N2

61 (22.2)

50.0

  

 N3

44 (16.2)

31.0

  

The 7th N stage (AJCC)

  

29.483

0.0003

 N0

66 (23.9)

66.0

  

 N1

44 (16.2)

66.7

  

 N2

71 (26.1)

48.1

  

 N3a

60 (21.8)

51.2

  

 N3b

33 (12.0)

20.8

  
  1. AJCC American Joint Committee on Cancer, N node