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Table 3 Logistic regression analysis of the number of cumulative MetS components and overall UC risk, non-muscle invasive bladder cancer (NMIBC) risk, and invasive bladder cancer (IBC) risk

From: The association between metabolic syndrome and the risk of urothelial carcinoma of the bladder: a case-control study in China

 

Number of metabolic risk factors

Dichotomously defined

0 components

1 component

2 components

≥3 components

MetS

No MetS

Overall UC

Controls (n)

355 (55.1)

363 (53.6)

220 (52.4)

160 (48.6)

  

UC cases (n)

289 (44.9)

314 (46.4)

200 (47.6)

169 (51.4)

  

P value

Ref

0.583

0.380

0.055

  

Crude OR (95 % CI)

Ref

1.063 (0.856–1.320)

1.117 (0.873–1.429)

1.297 (0.994–1.693)

  

Adjusteda P value

Ref

0.537

0.398

0.045

  

Adjusteda OR (95 % CI)

Ref

1.071 (0.862–1.331)

1.113 (0.869–1.425)

1.315 (1.006–1.719)

  

NMIBC

Controls (n)

355 (60.9)

363 (57.9)

220 (56.3)

160 (53.7)

160 (53.7)

938 (58.6)

UC cases (n)

228 (39.1)

264 (42.1)

171 (43.7)

138 (46.3)

138 (46.3)

663 (41.4)

P value

Ref

0.289

0.150

0.040

0.116

Ref

Crude OR (95 % CI)

Ref

1.132 (0.900–1.425)

1.210 (0.933–1.570)

1.343 (1.013–1.780)

1.220 (0.952–1.564)

Ref

Adjusteda P value

Ref

0.264

0.169

0.037

0.107

Ref

Adjusteda OR (95 % CI)

Ref

1.140 (0.906–1.436)

1.201 (0.925–1.559)

1.354 (1.019–1.798)

1.228 (0.957–1.577)

Ref

IBC

Controls (n)

355 (85.3)

363 (87.9)

220 (88.4)

160 (83.8)

160 (83.8)

938 (87.0)

UC cases (n)

61 (14.7)

50 (12.1)

29 (11.6)

31 (16.2)

31 (16.2)

140 (13.0)

P value

Ref

0.280

0.272

0.617

0.227

Ref

Crude OR (95 % CI)

Ref

0.802 (0.537–1.198)

0.767 (0.478–1.231)

1.128 (0.704–1.806)

1.298 (0.850–1.983)

Ref

Adjusteda P value

Ref

0.362

0.309

0.459

0.162

Ref

Adjusteda OR (95 % CI)

Ref

0.829 (0.553–1.241)

0.781 (0.485–1.257)

1.196 (0.744–1.924)

1.356 (0.885–2.077)

Ref

  1. MetS metabolic syndrome; UC urothelial carcinoma of bladder; NMIBC non-muscle invasive bladder cancer; IBC invasive bladder cancer
  2. aAdjusted for age (continuous), smoking status, gender