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Table 2 Surgical management and pathologic findings by the number of pulmonary metastases

From: The prognostic importance of the number of metastases in pulmonary metastasectomy of colorectal cancer

Characteristics

The number of pulmonary metastases

p valuea

All patients

Group I

Group II

Group III

 
 

N = 615

N = 414

N = 159

N = 42

 

No. of lungs resectedb, mean ± sd

1.92 ± 1.77

1.17 ± 0.46

2.64 ± 1.08

6.52 ± 3.31

<0.001

No. of lung metastasesc, mean ± sd

1.66 ± 1.44

1.0

2.28 ± 0.45

5.79 ± 2.62

<0.001

Difference between no. of lungs resected and no. of metastasesd, mean ± sd

0.25 ± 0.70

0.17 ± 0.46

0.33 ± 0.83

0.74 ± 145

<0.001

Maximum tumor size, mean ± sd

1.68 ± 1.23

1.64 ± 1.20

1.80 ± 1.34

1.67 ± 0.95

0.253

Bilaterality, n (%)

90 (14.6)

0

63 (39.6)

27 (64.3)

<0.001

Lymph node metastasis, n (%)e

    

0.614

 No lymph node dissection

439 (71.4)

303 (73.2)

108 (67.9)

28 (66.7)

 

 Lymph node dissection

176 (28.6)

111 (26.8)

51 (32.1)

14 (33.3)

 

  LN (−)

152 (24.7)

95

44

13

 

  LN (+)

24 (3.9)

16

7

1

 

Extent of resection, n (%)

    

0.442

 Precision excision

20 (3.3)

17

3

0

 

 Wedge resection

439 (71.4)

300

111

28

 

 Segmentectomy

41 (6.7)

24

15

2

 

 Lobectomy

109 (17.7)

71

26

12

 

 Bilobectomy/pneumonectomy

6 (0.9)

2

4

0

 

Surgical approach

    

<0.001

 Thoracotomy/sternotomy

244 (39.7)

118 (28.5)

93 (58.5)

33 (78.6)

 

 VATS

371 (60.3)

296 (71.5)

66 (41.5)

9 (21.4)

 
  1. aCorrelation between factors was assessed using χ 2 test and Student’s t test for continuous variables
  2. bNo. of lungs resected was defined as the number of pulmonary nodules resected in the operating room, not the number of pathologically confirmed metastatic lesions
  3. cNo. of lung metastases was defined as the number of pulmonary nodules that were pathologically confirmed to be metastatic cancer from CRC
  4. dDifference between no. of lungs resected and no. of lung metastases = (no. of lung resected) − (no. of lung metastases)
  5. eDefinitions: LN (+), thoracic lymph node dissection was performed, and at least one lymph node was positive for malignant cells; LN (−), thoracic lymph node dissection was performed, and at least one lymph node was negative for malignant cells; no lymph node dissection, thoracic lymph node dissection was not performed