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Table 3 Operative technique and postoperative results

From: Follicular thyroid carcinoma: differences in clinical relevance between minimally invasive and widely invasive tumors

Parameter MI-FTC WI-FTC p
42 29  
TT 40 (95.2 %) 21 (72.6 %)  
Completion thyroidectomy 2 (4.8 %) 3 (10.4 %)  
TT + CND 2 (6.8 %)  
TT + CND + MRND ipsilateral 1 (3.4 %)  
TT + CND + MRND bilateral 2 (6.8 %)  
Frozen section (true positive) 2 (4.8 %) 0  
Frozen section (false negative) 2 (4.8 %) 1 (3.4 %)  
Mean postoperative hospital stay    
(days) ± SD 3.7 ± 2.0 4.1 ± 2.5 0.520
Median (95 % CI) 3 (3.1–4.3) 3 (3.1–5.0)  
Morbidity    
  Transient hypocalcaemia 6 (14.2 %) 4 (13.8 %) 0.773
  Permanent hypocalcemia  
  Transient unilateral laryngeal nerve palsy  
  Permanent laryngeal nerve palsy 1 (3.4 %) 0.851
I131 ablation therapy    
  0 application
  1 application 37 (88.1 %) 22 (76.0 %) 0.209
  2 applications 5 (11.9 %) 4 (13.8 %) 0.898
  4 applications 1 (3.4 %) 0.064
  5 applications 1 (3.4 %)  
  8 applicationsa 1 (3.4 %)  
Tumor recurrence (node) 3 (10.4 %) 0.064
Lateral neck compartment 3 (10.4 %)  
Central neck compartment  
Loco-regional 1 (3.4 %)  
M1 at follow-up 3 (10.4 %) 0.064
Overall recurrence rate 7 (24.1 %) 0.001
Death of thyroid cancer  
Death of other causes  
Mean follow-up duration (months) (range) 113 (12–288) 125 (24–196)  
  1. MI-FTC minimally invasive - follicular thyroid carcinoma, WI-FTC widely invasive - follicular thyroid carcinoma, CND central neck dissection, MRND modified radical neck dissection, SD standard deviation, CI confidence interval, M1 metastasis to distant site
  2. aBone-marrow graft following aplastic anemia as side effect of multiple doses of RAI ablation therapy